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Highly active antiretroviral therapy (HAART) is a therapeutic intervention developed by clinicians and researchers in order to fight the HIV pandemic. It has contributed to a significant reduction in AIDS-related mortality and allowed many previously bed-ridden patients to live healthier, more productive lives. Until the advent of HAART in 1996, a diagnosis of HIV infection was considered a death sentence. A decade later, the disease has been transformed into a serious, yet potentially manageable, medical condition for thousands of people living with HIV/AIDS in the developed world - almost overnight creating a generation of "HIV Survivors" - and forged a global movement to ensure that its Lazarus-like benefit reaches millions more in the developing world. This book reviews the achievements of HAART over the past decade, and explores the challenges that may arise in the future. It recounts key landmarks in the development and introduction of HAART from the perspective of clinicians, researchers, economists, sociologists, and public policy experts, including the co-discoverers of HIV, Luc Montagnier and Robert Gallo.
It explores the evolution of the disease, the evolution of HIV treatment, and the economic, social, and public policy impacts of both HIV and the introduction of HAART.
Foreword ; 1. Introduction ; A DECADE OF HAART: TRIALS, TRIBULATIONS, AND SUCCESSES ; 2. A world ravaged by a disease without HAART ; 3. Turning the world on its ear: defining milestones on the road to HAART ; 4. Outcome and impact of 10 years of HAART ; 5. Highly Active Anti-Retroviral Therapy in HIV-infected children: a decade later ; HAART IN HIGH HUMAN DEVELOPMENT COUNTRIES ; 6. Country review: Australia ; 7. Country review: Chile ; 8. Country review: Germany ; 9. Country review: Italy ; 10. Country review: United States of America ; 11. The HIV Outpatient Study (HOPS) and the Multicenter AIDS Cohort Study ; 12. The French Hospital Database on HIV (FHDH) ANRS CO.4 ; 13. EuroSIDA: A prospective observational study of chronic HIV infection 13-1 Across the European continent ; 14. The Swiss HIV Cohort (SHCS) ; 15. The OPTIMA Cohort ; HAART IN MEDIUM HUMAN DEVELOPMENT COUNTRIES ; 16. Country review: Brazil ; 17. Country review: China ; 18. Country review: South Africa ; 19. Country review: Thailand ; 20. Cohort studies in Brazil: Projet Praca Onze ; 21. The HIV Netherlands-Australia-Thailand research collaboration (HIVNAT) ; HAART IN LOW HUMAN DEVELOPMENT COUNTRIES ; 22. Country review: Haiti ; 23. Country review: Malawi ; 24. Country review: Senegal ; 25. Country review: Zambia ; FUTURE CHALLENGES IN THE NEXT DECADE OF HAART ; 26. Clinical challenges of lifetime HAART ; 27. Maintaining and developing health systems to sustain HAART ; 28. Redefining HIV/AIDS care delivery in the face of human resource scarcity ; 29. Conclusion: closing the gap - one world, one standard
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- ID: 9780199225859
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