Neurogenesis in the adult brain has emerged as one of the most dynamic and rapidly moving fields in modern neuroscience research. The implications of adult neurogenesis for health and well-being are wide-ranging, with findings in this area having distinct relevance for treatment and rehabilitation in neurology and psychopathology. Adult Neurogenesis in the Hippocampus addresses these implications by providing an up-to-date account on how neurogenesis in the adult hippocampus contributes to critical psychological and physiological processes, such as learning and memory, and how it is modified by life experiences, such as aging, environmental enrichment, exercise, and dieting. The book also provides the most current reviews of how adult hippocampal neurogenesis influences the pathogenesis of mood disorders, addiction, and key neurological disorders. This book is the ideal resource for researchers and advanced graduates seeking focused knowledge on the role of adult neurogenesis in brain health and disease.
Dr. Juan J. Canales is a Reader in Behavioural Neuroscience in the Department of Neuroscience, Psychology and Behaviour at the University of Leicester (United Kingdom). Dr. Canales obtained his doctorate at the University of Oxford and after postdoctoral placements at the Massachusetts Institute of Technology (Cambridge, USA) and the Valencia Foundation for Biomedical Research (Spain), he became Ramon y Cajal Senior Scientist and later Institute Investigator at the University of Valencia (Spain). Before joining the University of Leicester, Dr. Canales was a Senior Lecturer in the Department of Psychology at the University of Canterbury (New Zealand). His research focuses on the neuropharmacology of drug addiction, the discovery of new targets for therapeutic intervention in addiction, and the involvement of postnatal neurogenesis in health and psychopathology.
Part I: Neurobiology and Physiology of Hippocampal Neurogenesis 1. Neurobiology of hippocampal neurogenesis Jose M. Garcia-Verdugo and Arturo Alvarez-Buylla 2. Physiology and plasticity Shaoyu Ge 3. Neurochemical and molecular regulation of hippocampal neurogenesis Sebastian Jessberger Part II: Neurogenesis in Health and Well-being 4. Learning and memory Martin Wojtowicz 5. Physical activity/enrichment Brian R. Christie 6. Nutrition and dieting Sandrine Thuret 7. Aging Sebastien Couillard-Despres Part III: Neurogenesis in Psychopathology and Disease 8. Depression Paul J. Lucassen 9. Anxiety and stress disorders Catherine Belzung 10. Addiction Amelia Eisch and Juan J. Canales 11. Neurological Disorders Kwok-Fai So