The optimal management of breast cancer patients relies on the expertise of a team of medical specialists including radiologists, surgeons, radiation therapists and medical oncologists. Much of the progress in breast cancer management made since the 1990s reflects the translation of observations made in the laboratory to the clinic. Critically evaluating the impact of new treatment approaches relies on a commitment to well-designed clinical trials. Topics covered include: management of menopausal symptoms; post mastectomy radiation therapy; preoperative chemotherapy; high dose chemotherapy; system adjuvant therapy; biological therapies; and chemoprevention. This work gathers a renowned group of breast cancer experts and provides their perspectives on management issues that directly affect patients on a day-to-day basis.