Adverse Drug Interactions: A Handbook for Prescribers, Second Edition (2nd Revised edition)

Adverse Drug Interactions: A Handbook for Prescribers, Second Edition (2nd Revised edition)

By: Janaka Karalliedde (editor), Simon F. J. Clarke (editor), Ursula Collignon (editor), Lakshman Delgoda Karalliedde (editor)Paperback

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Description

Adverse Drug Interactions: A Handbook for Prescribers assists clinicians by providing key information on potential adverse effects that can result from prescribing two or more drugs for simultaneous use. Interactions that are likely to give rise to life-threatening conditions, and which must therefore be completely avoided, are clearly highlighted. Less threatening but nonetheless important interactions necessitating practical measures, such as frequent monitoring and advice to patients, are also discussed. Presented in a user-friendly format, the book is organised by drug class and provides a brief summary of the mechanism underlying a particular interaction, alternative drugs lacking the same reactions that may be considered, and instructions for monitoring patients when adverse effects occur. All interactions listed in the previous edition have been reviewed and updated using the latest information available. The clinical reality of the widespread use of potent medicines, whether allopathic, herbal or traditional, has led to the inclusion of a chapter specifically addressing over-the-counter drugs and remedies. Importantly, the increasing relevance of drug interactions due to genetic polymorphisms of metabolizing enzymes and drug transporters and the associated influence of these in ethnic groups is discussed. Also discussed is the risk of interactions in many vulnerable population groups (e.g. infancy, pregnancy, infections, liver and kidney disease). This quick and easy reference guide brings together the current evidence base with a broad range of practical prescribing experience to produce a source of advice that can be used in the clinic, pharmacy, or at the patient's bedside.

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About Author

Edited by Lakshman Delgoda Karalliedde, visiting professor, Faculty of Medicine Peradeniya, Sri Lanka, and visiting senior lecturer, King's College London, UK Simon Clarke, Frimley Park NHS Foundation Trust, Camberley, UK Ursula Gotel nee Collignon, St. Thomas' Hospital, London, UK Janaka Karalliedde, King's College London School of Medicine, UK

Contents

Drugs Acting on the Cardiovascular System Simon F.J. Clarke Drugs Acting on the Central Nervous System Lakshman Delgoda Karalliedde and Harini Genegedera Anticancer and Immunomodulating Drugs Patrick Yong Anticoagulants Rebecca Chanda Antidiabetic Drugs Yohan P. Samarasinghe and Janaka Karalliedde Other Endocrine Drugs Ming Ming Teh and Yohan P. Samarasinghe Analgesics Ruwan Parakramawansha Musculoskeletal Drugs Winglam Yeung Anesthetic Drugs: General Vasanthi Pinto and E. Queenie Veerasingam Drugs to Treat Infections Ursula Collignon Drugs Acting on the Gastrointestinal Tract Ursula Collignon Respiratory Drugs Lakshman Delgoda Karalliedde and Simon F.J. Clarke Metabolic Drugs Simon F.J. Clarke Obstetrics and Gynecology Gregory Ian Giles and Simon F.J. Clarke Drugs Used to Treat the Urinary System Simon F.J. Clarke Drugs of Abuse Lakshman Delgoda Karalliedde and Janaka Karalliedde Miscellaneous Lakshman Delgoda Karalliedde, Janaka Karalliedde, and Seneka Abeyratne Over-the-Counter/Online Drugs, Traditional and Herbal Remedies Lakshman Delgoda Karalliedde, Janaka Karalliedde, and Seneka Abeyratne Appendices: Factors Associated with Drug Effects Simon F.J. Clarke, Lakshman Delgoda Karalliedde, and Ursula Collignon Factors Associated with Interactions (Polymorphisms, Ethnicity, Age, Disease States) Simon F.J. Clarke, Lakshman Delgoda Karalliedde, and Ursula Collignon Foods Implicated in Potentially Severe Interactions Lakshman Delgoda Karalliedde, Janaka Karalliedde, and Seneka Abeyratne Clinical Drug Development Lakshman Delgoda Karalliedde and Janaka Karalliedde Assessments of Manifestations of DDIs Simon F.J. Clarke and Ursula Collignon Triptan Sensations Lakshman Delgoda Karalliedde and Janaka Karalliedde Assessment of Severity of Liver Disease Chulananda Goonasekera Prescribing Guidelines for Elderly Patients Andrea Corsonello and Giuseppe Maltese Factors Affecting Efficacy of Anti-Infective Agents Niroshini Manthri Giles and Lakshman Delgoda Karalliedde Assessments of Obesity Lakshman Delgoda Karalliedde and H.M.U. Amila Jayasinghe

Product Details

  • publication date: 29/06/2016
  • ISBN13: 9781482236217
  • Format: Paperback
  • Number Of Pages: 1211
  • ID: 9781482236217
  • weight: 2040
  • ISBN10: 1482236214
  • edition: 2nd Revised edition

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