An Introduction to Forensic DNA Analysis (2nd Revised edition)
By: Norah Rudin (author), Keith Inman (author)Hardback
4 - 6 days availability
Significant advances in DNA analysis techniques have surfaced since the 1997 publication of the bestselling An Introduction to Forensic DNA Analysis. DNA typing has become increasingly automated and miniaturized. Also, with the advent of Short Tandem Repeat (STR) technology, even the most minute sample of degraded DNA can yield a profile, providing valuable case information. However, just as the judicial system slowly and reluctantly accepted RFLP and AmpliType(R) PM+DQA1 typing, it is now scrutinizing the admissibility of STRs. Acknowledging STR typing as the current system of choice, An Introduction to Forensic DNA Analysis, Second Edition translates new and established concepts into plain English so that laypeople can gain insight into how DNA analysis works, from sample collection to interpretation of results. In response to the shift toward more efficient techniques, the authors cover the legal admissibility of STR typing, expand the chapter on DNA databases, and revise the section on automated analysis. They also present key decisions and appellate or supreme court rulings that provide precedent at the state and federal levels.
Discussing forensic DNA issues from both a scientific and a legal perspective, the authors of An Introduction to Forensic DNA Analysis, Second Edition present the material in a manner understandable by professionals in the legal system, law enforcement, and forensic science. They cover general principles in a clear fashion and include a glossary of terms and other useful appendices for easy reference.
Introduction The Nature of Physical Evidence Science and the Law Principles and Processes of Criminalistics Fingerprints and DNA Conventional Blood Typing The Collection and Preservation of Physical Evidence Extraneous Substances Collection of Evidence Preservation of Evidence Evaluation of Evidence A Short History of DNA Typing The Scientific Basis of DNA Typing Why DNA? An Introduction to Human Genetics An Introduction to the Molecular Biology of DNA Two Kinds of Variation Enzymes, the Workhorses of the Biological World An Overview of Forensic DNA Typing Systems RFLP Analysis PCR Amplification What Kinds of Samples Can be Analyzed? How Much Sample Do You Need? Procedures for Forensic DNA Analysis Isolation of DNA Determining Quality and Quantity of DNA RFLP Analysis PCR Amplification Analysis of PCR Product Automated Analysis Systems Interpretation of DNA Typing Results Complicating Factors System Specific Interpretational Issues Summary of DNA Interpretation Issues Assessing the Strength of the Evidence Determination of Genetic Concordance Evaluation of Results Frequency Estimate Calculations Population Substructure Likelihood Ratios When is a DNA Profile Unique? The DNA Databank Premise of a Databank The Difference between a Databank and a Database Elements of a Successful Databank Summary Quality Assurance Certification and Accreditation SWDAM (formerly TWGDAM) NRC I and II Federal DNA Advisory Board Admissibility Standards - Science on Trial in the Courtroom Frye, Daubert, and the Federal Rules of Evidence DNA - Some Landmark Cases The State of the Debate Epilogue Glossary Appendices
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- ID: 9780849302336
2nd Revised edition
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