Caldesmon is one of the most abundant proteins detected in smooth muscle and in a number of non-muscle cells. It binds actin, myosin, tropomyosin and calmodulin and is believed to play in smooth muscle a regulatory role similar to that of troponin in striated muscle. Two closely-related isoforms of caldesmon being the products of an alternative splicing of a single gene, have been identified. The high molecular weight (H-CaD) isoform is expressed predominantly in smooth muscle, whereas the low molecular weight (L-CaD) isoform is found in non-muscle tissues and cells. This book examines the anatomy and physiology of caldesmon proteins.
- Contributor: Edward A Czurylo
- Imprint: Nova Science Publishers Inc
- ISBN13: 9781613243121
- Number of Pages: 123
- Packaged Dimensions: 230x155mm
- Packaged Weight: 220
- Format: Paperback
- Publisher: Nova Science Publishers Inc
- Release Date: 2012-05-18
- Binding: Paperback / softback
We hope you are delighted with everything you buy from us. However, if you are not, we will refund or replace your order up to 30 days after purchase. Terms and exclusions apply; find out more from our Returns and Refunds Policy.