Assisted Reproductive Technology: Accomplishments and New Horizons

Assisted Reproductive Technology: Accomplishments and New Horizons

By: Christopher J. De Jonge (editor), Christopher L. R. Barratt (editor)Hardback

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This insightful and thought-provoking 2002 collection of chapters describes the rapid advances that had revolutionised reproductive medicine in the years leading up to its publication. This transformation was the result of converging and overlapping developments in reproductive biology, molecular biology and genetics. These advances allied with remarkable technical developments pushed the boundaries of this discipline ever faster forward. This volume surveys this rapid expansion as it stood in 2002 and looks ahead at exciting prospects for the future that stand at the watershed between basic science and clinical application. From oogeneis and spermatogenesis, through to fertilisation, embryogenesis and cloning, this volume looks at scientific advances. Subsequent chapters focus on infertility and its diagnosis and treatment using the full armory of assisted reproductive technologies. A concluding section surveys the impact of these developments on the provision, regulation and financing of reproductive health care in the global community.

About Author

Professor Christopher De Jonge is Director of Laboratories at the Reproductive Medicine Center Department of Obstetrics and Gynecology, University of Minnesota. Professor Christopher Barratt is Scientific Director at the Assisted Conception Unit, Birmingham Women's Hospital.


Foreword Howard W. Jones; Part I. The Gametes: Present and Future: 1. Spermatogenesis in vitro in mammals Bernard Jegou, Charles Pineau and Jorma Toppari; 2. The spermatozoon as a machine J. Travis and Gregory Kopf; 3. Attributes of fertile spermatozoa Christopher De Jonge and Christopher L. R. Barratt; 4. In vitro oogenesis Frank L. Barnes; 5. The oocyte as a machine Kate Hardy; 6. Epigenetic influences on human oocyte and embryo development Jonathan Van Blerkom; 7. Unresolved and basic problems in assisted reproductive technology Jim Cummins; Part II. Techniques: Present and future: 8. Influences of culture media on embryo development Barry Bavister and Jay Baltz; 9. Cryopreservation of immature and mature gametes John K. Critser, Yuksel Agca and Erik J. Woods; 10. Embryonic stem cells Ann M. Lawler and John D. Gearhart; 11. Modification of the male genome by gene and spermatogonial transplantation Peter J. Donovan, Michael D. Griswold and Lonnie D. Russell; 12. Genetic diagnosis - the future David Cram and David de Kretser; 13. Cloning mammals Don P. Wolf and Shoukhrat Mitalipov; 14. Fluorescence imaging: gamete selection and ICSI L. Hewitson, C. Simerly and G. Schatten; Part III. The Clinic: 15. Diagnosis and treatment of male infertility A. Kamischke and E. Nieschlag; 16. Tests of male fertility R. John Aitken; 17. Diagnosis and treatment for female subfertility Peter Platteau and Paul Devroey; 18. Advances in ultrasound imaging Richard P. Dickey and Ellen Matulich; 19. The natural cycle vs stimulated cycle Ian D. Cooke; 20. Embryo stage and transfer number Alan Trounson; 21. The national institutes of health and the research base for improving the outcomes of ART Donna L. Vogel; Part IV. Concepts for the Global Community: 22. From conception to contraception Gustavo F. Doncel, Christine Mauck, Douglas S. Colvard and Lourens J. D. Zaneveld; 23. Developing immunocontraceptives Eileen A. McLaughlin and Michael K. Holland; 24. ARTistic license: should assisted reproductive technologies be regulated? Nanette R. Elster; 25. Finances and access to ART: justice and publication of results F. Shenfield; 26. Sex selection Joe Leigh Simpson and Sandra Ann Carson; 27. ICSI: a time bomb? Herman J. Tournaye and Andre C. Van Steirteghem; 28. Cryopreservation of gametes and embryos - legal and ethical aspects Susan M. Avery and Peter R. Brinsden; Index.

Product Details

  • ISBN13: 9780521801218
  • Format: Hardback
  • Number Of Pages: 446
  • ID: 9780521801218
  • weight: 1224
  • ISBN10: 0521801214

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