Here, all aspects of the topic are presented in a compact manner. The book is clearly structured, and divided into two sections -- asymmetric synthesis of heterocycles containing only one nitrogen and that of those with more than one nitrogen as a heteroatom -- such that the necessary information may be found at a glance. The international team of authors provides important experimental procedures, including industrial applications. Essential for synthetic chemists in pharmaceutical and agrochemical chemistry.
Jacques Royer is Director of Research at the CNRS. He is currently the head of a laboratory of medicinal chemistry at the University Paris Descartes. He got his PhD at the University of Paris-Sud Orsay, and worked for 18 years at the Institut de Chimie des Substances Naturelles at the CNRS in Gif-sur-Yvette in the group of Prof. Henri-Philippe Husson. His research areas are asymmetric synthesis of natural products and more particularly alkaloids, amino alcohols and amino acids as well as original methods of synthesis including electrosynthesis. He is the author of about 100 publications in international renowned journals.
PART 1: Asymmetric Synthesis of Nitrogen Heterocycles Containing Only One Heteroatom ASYMMETRIC SYNTHESIS OF THREE- AND FOUR-MEMBERED RING HETEROCYCLES Substituted Aziridines Substituted Monocyclic Azetidines and Carbocyclic-Fused Systems ASYMMETRIC SYNTHESIS OF FIVE-MEMBERED RING HETEROCYCLES Monocyclic Pyrrolidines and Pyrrolidinones Pyrrolines Fused Bicyclic Systems with Bridgehead Nitrogen ASYMMETRIC SYNTHESIS OF SIX-MEMBERED RING HETEROCYCLES Introduction Dihydropyridines Tetrahydropyridines Monocyclic Piperidines and Carbocyclic Fused Systems Fused Tri- or Bicyclic System with Bridgehead Nitrogen ASYMMETRIC SYNTHESIS OF SEVEN- AND MORE-MEMBERED RING HETEROCYCLES Substituted Azepines Substituted Azocines Substituted Large Nitrogen-Containing Rings PART 2: Asymmetric Synthesis of Nitrogen Heterocycles With More Than One Heteroatom ASYMMETRIC SYNTHESIS OF THREE- AND FOUR-MEMBERED RING HETEROCYCLES WITH MORE THAN ONE HETEROATOM Introduction Three-Membered N-Heterocycles with Two Heteroatoms Four-Membered N-Heterocycles with Two Heteroatoms ASYMMETRIC SYNTHESIS OF FIVE-MEMBERED RING HETEROCYCLES WITH MORE THAN ONE HETEROATOM Five-Membered Heterocycles with N and O Atoms Five-Membered Heterocycles with Two N Atoms Five-Membered Heterocycles with N and S Atoms ASYMMETRIC SYNTHESIS OF SIX-MEMBERED RING NITROGEN HETEROCYCLES WITH MORE THAN ONE HETEROATOM Six-Membered Rings with Another Heteroatom in the Same Ring ASYMMETRIC SYNTHESIS OF SEVEN-MEMBERED RINGS WITH MORE THAN ONE HETEROATOM Diazepines Oxazepines Thiazepines