William Clark's At War Within takes us on a fascinating tour through the immune system, examining the history of its discovery, the ways in which it protects us, and how it may bring its full force to bear at the wrong time or in the wrong place.
Scientists have only gradually come to realize that this elegant defence system not only has the potential to help, as in the case of smallpox, but also the potential to do profound harm in health problems ranging from allergies to AIDS, and from organ transplants to cancer. Dr Clark discusses the myriad of medical problems involving the immune system, and systematically explains each one, making the complexities of this delicately balanced mechanism comprehensible to the lay
William R. Clark has taught immunology at the University of California for over twenty years, and is the author of one of the standard textbooks in the field. He is an internationally recognized authority on cellular immune responses, and has published many papers on the subject.
Chapter 1: Overture to a science unborn: Smallpox and the origins of immunology ; Chapter 2: The anatomy of an immune response ; Chapter 3: Living in the bubble: Primary immune deficiency diseases ; Chapter 4: Hypersensitivity and allergy ; Chapter 5: Horror autotoxicus: The immunology of self-destruction ; Chapter 6: When the wall comes tumbling down ... AIDS ; Chapter 7: Organ transplantation: Technology vs. ethics? ; Chapter 8: Minding the immune system's business: The dialogue between the brain and the immune system ; Appendix: Diversity, tolerance and memory: The intellectual history of immunology