This richly illustrated book presents the pediatric applications of PET/CT in the full range of scenarios frequently encountered in a professional setting. It opens with a thorough introduction covering the fundamental science and the clinical basis for use of PET/CT in this age group. Pitfalls and artifacts are examined, and normal variations and benign findings are carefully described. Each subsequent chapter addresses the role of PET/CT with different radiopharmaceuticals in the evaluation and management of a specific disease. The full range of oncological diseases is covered, including the rare ones. Succinct descriptions of clinical cases are included and, when appropriate, comparisons are made with other modalities. In addition, the role of PET/CT in biopsy guidance and in radiation therapy planning is explained. This book will be invaluable for residents and practitioners in nuclear medicine, radiology, oncology, radiation oncology, and nuclear medicine technology
Section I Basic Science and Practical Issues 1 Radiofarmaceutical Compounds.- 2 Method and Preparation of the Patient.- 3 18F-FDG Administration and Dosimetry.- 4 Physiological Pattern and Pitfall of 18F-FDG Biodistribution.- Section II Oncology 5 Malignant Lymphoma in Children.- 6 18-FDG PET/CT in Pediatric Lymphoma.- 7 Other Haematological Diseases (Leukemia).- 8 Primary Bone Tumors.- 9 Utility of 18F-FDG PET/CT in Soft Tissue Sarcomas.- 10 Primary Hepatic Tumors.- 11 Neuroendocrine Tumors.- 12 Neuroblastoma.- Other Tumors 13 Pediatric Nasopharyngeal Carcinoma.- 14 Poorly Differentiated Thyroid Carcinoma.- 15 Phylloid Tumor of the Breast.- 16 Wilms Tumor.- 17 Adrenal Gland Cancer.- 18 Ovarian Teratoma.- Section III Neurology 19 Role of Aminoacid PET Tracers in Pediatric Brain Tumors.- 20 18F-FDG in Brain Tumors.- 21 PET/CT in the Clinical Evaluation of Pediatric Epilepsy.- 22 Epilepsia Partialis Continua.- 23 Brain 18F- FDG PET/CT Imaging in Haemolytic Uraemic Syndrome (HUS) During and After the Acute Phase.- Section IV Infection and Inflammation 24 Inflammatory Bowel Disease.- 25 Appendicitis.- 26 Spondylodiscitis.- 27 Other Bone Lesion.- 28 Pulmonary Aspergillosis.- 29 Mycobatteriosis.- Section V Other Applications 30 Sarcoidosis.- 31 Neurofibromatosis.- 32 Autoimmune Lymphoproliferative Syndrome (ALPS). 33 Castelman's Disease.- 34 Fever of Unknown Origin.- 35 Congenital Hyperinsulinism.- 36 Myocardial Perfusion Imaging with Rb Cardiac PET/CT.