Bioactive Heterocyclic Compound Classes: Pharmaceuticals and Agrochemicals, 2 Volume Set

Bioactive Heterocyclic Compound Classes: Pharmaceuticals and Agrochemicals, 2 Volume Set

By: Jurgen Dinges (editor), Clemens Lamberth (editor)Hardback

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Description

Filling a gap in the market, this two-volume set is the first to present important pharmaceuticals as well as agrochemical pesticides in one handy work. Each of the around 40 chapters covers in a concise manner one class of heterocycles, clearly structured as follows: * Structural formulas of most important examples (market products) * Short background of history or discovery * Typical syntheses of important examples * Mode of action * Characteristic biological activity * Structure-activity relationship * Additional chemistry information (e.g. further transformations, alternative syntheses, metabolic pathways, etc.) * References. A valuable one-stop reference source for researchers in academia and industry as well as for graduate students with career aspirations in the field of pharmaceutical and agrochemical chemistry.

About Author

Clemens Lamberth is a senior team leader in the crop protection research department of Syngenta AG, Switzerland. He studied chemistry at the Technical University of Darmstadt, Germany, where he obtained his Ph.D. under the supervision of Prof. Bernd Giese in 1990. Subsequently, he spent one and a half years as a postdoctoral fellow in the group of Prof. Mark Bednarski at the University of California at Berkeley (USA). In 1992 Clemens Lamberth joined the agrochemical research department of Sandoz Agro AG, Switzerland, which is today, after two mergers, part of Syngenta Crop Protection AG. Since 20 years he is specialized in fungicide discovery. He was the organizer of the two-day session "New Trends for Agrochemicals" at the 2nd EUCHEMS congress in Torino, Italy, 2008. He is the author of 46 publications and 56 patents and the inventor of Syngenta's fungicide mandipropamid (Revus(R), Pergado(R)). Jurgen Dinges obtained his M.S. degree in organic chemistry at the Technical University in Darmstadt, Germany, in 1988. He then joined the group of Prof. Frieder W. Lichtenthaler at the same university, where he received his Ph.D. degree in organic chemistry and chemical engineering in 1991. After being awarded a Feodor-Lynen scholarship from the Humboldt foundation, he spent 18 months as a postdoctoral fellow in the group of Prof. William G. Dauben at the University of California at Berkeley (USA). In 1993, Jurgen Dinges joined the department for biochemistry at Syntex, USA and since 1995 he is working in the pharmaceutical research department at Abbott Laboratories, USA. During his 18 years of industrial experience, Jurgen Dinges has specialized in drug discovery. In 2009, he was a guest editor for "Current Topics in Medicinal Chemistry" for a special issue on Parkinson's disease. He is an author of 17 publications and 23 patents and a co-inventor of more than 10 clinical drug development candidates.

Contents

INTRODUCTION I. PHARMACEUTICALS NEUROLOGICAL DISORDERS Tropanes Morphines Barbituric Acid Phenothiazine Aryl Piperazines Aryl Piperidines Benzazepines CARDIOVASCULAR DISEASES Dihydropyridines Tetrazoles Thiazides Tetrahydropyranones INFECTIOUS DISEASES Adenines Guanines Penicillins and Cephalosporins ONCOLOGY Pyrimidines Triazoles INFLAMMATION AND GASTROINTESTINAL DISEASES Glucocorticoids Benzimidazoles METABOLIC DISEASES Thiazolidinediones II. AGROCHEMICALS INTRODUCTION HERBICIDES Triazines Pyrimidine and Triazine Sulfonylureas Triazolopyrimidines Benzoylpyrazoles Pyridyloxyphenoxypropionates Imidazolinones Uracils FUNGICIDES Benzimidazoles Morpholines Triazoles Anilinopyrimidines Phenylpyrroles Pyrimidine Strobilurins Pyrazole carboxamides INSECTICIDES Avermectins Pyridine and Thiazole Neonicotinoids Pyrazole and Pyrimidine Acaricides Phenylpyrazole Fiproles Pyrazolylpyridine Diamides Tetronic Acids

Product Details

  • ISBN13: 9783527329939
  • Format: Hardback
  • Number Of Pages: 670
  • ID: 9783527329939
  • weight: 1582
  • ISBN10: 3527329935

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