Bioinorganic photochemistry is a rapidly evolving field integrating inorganic photochemistry with biological, medical and environmental sciences. The interactions of light with inorganic species in natural systems, and the applications in artificial systems of medical or environmental importance, form the basis of this challenging inter-disciplinary research area. Bioinorganic Photochemistry provides a comprehensive overview of the concepts and reactions fundamental to the field, illustrating important applications in biological, medical and environmental sciences. Topics covered include:* Cosmic and environmental photochemistry* Photochemistry of biologically relevant nanoassemblies* Molecular aspects of photosynthesis* Photoinduced electron transfer in biosystems* Modern therapeutic strategies in photomedicine The book concludes with an outlook for the future of environmental protection, discussing emerging techniques in the field of pollution abatement, and the potential for bioinorganic photochemistry as a pathway to developing cheap, environmentally friendly sources of energy.
Written as an authoritative guide for researchers involved in the development of bioinorganic photochemical processes, Bioinorganic Photochemistry is also accessible to scientists new to the field, and will be a key reference source for advanced courses in inorganic, and bioinorganic chemistry.
Dr Grazyna Stochel, Deputy Dean, Faculty of Chemistry, Jagiellonian University, Cracow, Poland
Part I. Introduction 1. Philosophy of bioinorganic photochemistry Part II. Fundamentals 2. Light and matter 2.1. Nature of light 2.2. Accessible light sources 2.3. Interaction between light and matter 3. Formation and properties of electronic excited states 3.1. Wave mechanics and quantum numbers 3.2. Electronic excitation 4. Photophysical deactivation of electronic excited states 4.1. Spontaneous deactivation 4.2. Quenching 4.3. Coordination and organometallic compounds 5. Kinetics of the excited-state decay 6. Photochemical reactions 6.1.Photochemical reaction channels 6.2. Intramolecular photoreactions 6.3. Intermolecular photoreactions 6.4. The coordination compound specificity 6.5. Photosensitization 6.6. Homogeneous photocatalysis 7. Photochemistry and photophysics of supramolecular systems and nanoassemblies 7.1. From molecules through clusters to crystals 7.2. Metallic nanoparticles: metals in the embryonic state 7.3. Formation and decay of the excited states of semiconductors Part III. Natural photoprocesses involving inorganic compounds 8. From interstellar space to planetary atmospheres 8.1. Homogeneous systems: From interstellar space to planetary atmospheres and primitive soup models 8.2. Heterogeneous photochemistry in ice phases 9. Solar radiation and terrestrial environment 9.1. Solar radiation 9.2. Atmospheric photochemistry 9.3. Photochemistry in hydrosphere and lithosphere 9.4. Photochemical self-cleaning in the environment 10. Heretogeneous (photo)catalysis and biogenesis on Earth 10.1. (Photo)catalysis on chalcogenide semiconductors 10.2. Photocatalytic nitrogen fixation 10.3. Photocatalytic carbon dioxide fixation 10.4. "Fossils" of prebiotic catalysts: metal clusters in active centres of metalloenzymes 11. Foundation and evolution of photosynthesis 11.1. Photosynthetic structures 11.2. Oxygenic photosynthesis 11.3. Light harvesting antennas (LHC) 11.4. Electron transfer pathways in PSII and PSI 11.5. Oxygen evolving complex, OEC Part IV. Photochemistry and photophysics in bioinspired systems. Studies and modeling 12. Photoenzymes 12.1. Natural photoenzymes 12.2. Modified natural proteins/enzymes 12.3. Artificial photoenzymes 12.4. Towards mimicking the photosynthetic processes 13. Photoinduced electron transfer in proteins 13.1. Photochemical methodology 13.2. Biochemical applications 14. Nucleic acids photocleavage and charge transport 14.1. Mechanisms and strategies for advanced metallophotocleavers 14.2. Photoinduced DNA-mediated charge transport Part V. Towards applications 15. Light and biomatter (molecules, cells and tissues) 16. Fluorescent and chromogenic sensing and labeling 16.1. Cations as targets in biochemical sensing 16.2. Fluorescent and chromogenic sensing of anions 16.3. Optical detection of neutral molecules 16.4. Nanoparticles in biochemical sensing and labeling 17. Therapeutic strategies 17.1. Photobiostimulation 17.2. Photoactivation of drugs 17.3. Photodynamic therapy 17.4. Nanomedicine methods 18. Photodynamic inactivation 19. Photodelivery and phototargeting 20. Phototoxicity and photoprotection 20.1. Chemical and physical photoprotection 20.2. Inorganic sunscreens 21. Photocatalysis in the environmental protection 21.1. Development of homo- and heterogeneous methods 21.2. Homogeneous photocatalysis 21.2. Heterogeneous systems 21.3.New ideas in pollution abatement