Cell Biology (3rd Revised edition)

Cell Biology (3rd Revised edition)

By: Thomas D. Pollard (author), Graham Johnson (author), William C. Earnshaw (author), Jennifer Lippincott-Schwartz (author)Hardback

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Description

The much-anticipated 3rd edition of Cell Biology delivers comprehensive, clearly written, and richly illustrated content to today's students, all in a user-friendly format. Relevant to both research and clinical practice, this rich resource covers key principles of cellular function and uses them to explain how molecular defects lead to cellular dysfunction and cause human disease. Concise text and visually amazing graphics simplify complex information and help readers make the most of their study time. Clearly written format incorporates rich illustrations, diagrams, and charts. Uses real examples to illustrate key cell biology concepts. Includes beneficial cell physiology coverage. Clinically oriented text relates cell biology to pathophysiology and medicine. Takes a mechanistic approach to molecular processes. Major new didactic chapter flow leads with the latest on genome organization, gene expression and RNA processing. Boasts exciting new content including the evolutionary origin of eukaryotes, super resolution fluorescence microscopy, cryo-electron microscopy, gene editing by CRISPR/Cas9, contributions of high throughput DNA sequencing to understand genome organization and gene expression, microRNAs, IncRNAs, membrane-shaping proteins, organelle-organelle contact sites, microbiota, autophagy, ERAD, motor protein mechanisms, stem cells, and cell cycle regulation. Features specially expanded coverage of genome sequencing and regulation, endocytosis, cancer genomics, the cytoskeleton, DNA damage response, necroptosis, and RNA processing. Includes hundreds of new and updated diagrams and micrographs,plus fifty new protein and RNA structures to explain molecular mechanisms in unprecedented detail. Student Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and over a dozen animations from the book on a variety of devices.

Contents

Section 1: Introduction to Cell Biology 1 Introduction to Cells 2 Evolution of Life on Earth Section 2: Chemical and Physical Background 3 Molecules: Structures and Dynamics 4 Biophysical Principles 5 Macromolecular Assembly 6 Research Strategies Section 3: Chromatin, Chromosomes, and the Cell Nucleus 7 Chromosome Organization 8 DNA Packaging in Chromatin and Chromosomes 9 Nuclear Structure and Dynamics Section 4: Central Dogma: From Gene to Protein 10 Gene Expression 11 Eukaryotic RNA Processing 12 Protein Synthesis and Folding Section 5: Membrane Structure and Function 13 Membrane Structure and Dynamics 14 Membrane Pumps 15 Membrane Carriers 16 Membrane Channels 17 Membrane Physiology Section 6: Cellular Organelles and Membrane Trafficking 18 Posttranslational Targeting of Proteins 19 Mitochondria, Chloroplasts, Peroxisomes 20 Endoplasmic Reticulum 21 Secretory Membrane System and Golgi Apparatus 22 Endocytosis and the Endosomal Membrane 23 Processing and Degradation of Cellular Components Section 7: Signaling Mechanisms 24 Plasma Membrane Receptors 25 Protein Hardware for Signaling 26 Second Messengers 27 Integration of Signals Section 8: Cellular Adhesion and the Extracellular Matrix 28 Cells of the Extracellular Matrix and Immune System 29 Extracellular Matrix Molecules 30 Cellular Adhesion 31 Intercellular Junctions 32 Connective Tissues Section 9: Cytoskeleton and Cellular Motility 33 Actin and Actin-Binding Proteins 34 Microtubules and Centrosomes 35 Intermediate Filaments 36 Motor Proteins 37 Intracellular Motility 38 Cellular Motility 39 Muscles Section 10: Cell Cycle 40 Introduction to the Cell Cycle 41 G1 Phase and Regulation of Cell Proliferation 42 S Phase and DNA Replication 43 G2 Phase and Control of Entry into Mitosis 44 Mitosis and Cytokinesis 45 Meiosis 46 Programmed Cell Death Glossary Appendix

Product Details

  • ISBN13: 9780323341264
  • Format: Hardback
  • Number Of Pages: 908
  • ID: 9780323341264
  • ISBN10: 0323341268
  • edition: 3rd Revised edition

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