Comprehensive Handbook of Alcohol Related Pathology (Special ed.)

Comprehensive Handbook of Alcohol Related Pathology (Special ed.)

By: Victor R. Preedy (editor), Ronald Ross Watson (editor)Hardback

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This comprehensive handbook is a "one-stop-shop" for all researchers involved in the field of alcohol-related harm at the whole body or cellular level. Over 100 chapters provide abundant information of a wide range of topics that extend from the evolutionary aspects of alcohol consumption and the prevalence of alcohol misuse to programmed cell death. Each chapter is highly illustrated with tables and figures making this a valuable reference for students, clinicians and researchers alike.

About Author

Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRCPath, FRSC is a senior member of King's College London. He is also Director of the Genomics Centre and a member of the Faculty of Life Sciences and Medicine. Professor Preedy has longstanding academic interests in substance misuse especially in relation to health and well being. He is a member of the Editorial Board of Drug and Alcohol Dependence and a founding member of the Editorial Board of Addiction Biology. In his career Professor Preedy was Reader at the Addictive Behaviour Centre at The University of Roehampton, and also Reader at the School of Pharmacy (now part of University College London; UCL). Professor Preedy is Editor of the influential works The Handbook Of Alcohol Related Pathology, The Neuropathology of Drug Addictions and Substance Misuse and The Handbook of Cannabis and Related Pathologies (all published by Academic Press-Elsevier). Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981. In 1992, he received his Membership of the Royal College of Pathologists and in 1993 he gained his second doctoral degree (DSc). Professor Preedy was elected as a Fellow of the Institute of Biology in 1995 and also as a Fellow to the Royal College of Pathologists in 2000. He was then elected as a Fellow of the Royal Society for the Promotion of Health (2004) and The Royal Institute of Public Health and Hygiene (2004). In 2009, Professor Preedy became a Fellow of the Royal Society for Public Health and in 2012 a Fellow of the Royal Society of Chemistry. To his credit, Professor Preedy has published over 600 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and numerous books and volumes. Ronald Ross Watson PhD is a professor of Health Promotion Sciences in the University of Arizona Mel and Enid Zuckerman College of Public Health. He was one of the founding members of this school serving the mountain west of the USA. He is a professor of Family and Community Medicine in the School of Medicine at the University of Arizona. He began his research in public health at the Harvard School of Public Health as a fellow in 1971 doing field work on vaccines in Saudi Arabia. He has done clinical studies in Colombia, Iran, Egypt, Saudi Arabia, and USA which provides a broad international view of public health. He has served in the military reserve hospital for 17 years with extensive training in medical responses to disasters as the chief biochemistry officer of a general hospital, retiring at a Lt. Colonel. He published 450 papers, and presently directs or has directed several NIH funded biomedical grants relating to alcohol and disease particularly immune function and cardiovascular effects including studying complementary and alternative medicines. Professor Ronald Ross Watson was Director of a National Institutes of Health funded Alcohol Research Center for 5 years. The main goal of the Center was to understand the role of ethanol-induced immunosuppression on immune function and disease resistance in animals. He is an internationally recognized alcohol-researcher, nutritionist and immunologist. He also initiated and directed other NIH-associated work at The University of Arizona, College of Medicine. Dr. Watson has funding from companies and non-profit foundations to study bioactive foods' components in health promotion. Professor Watson attended the University of Idaho, but graduated from Brigham Young University in Provo, Utah, with a degree in Chemistry in 1966. He completed his Ph.D. degree in 1971 in Biochemistry from Michigan State University. His postdoctoral schooling was completed at the Harvard School of Public Health in Nutrition and Microbiology, including a two-year postdoctoral research experience in immunology. Professor Watson is a distinguished member of several national and international nutrition, immunology, and cancer societies. Overall his career has involved studying many foods for their uses in health promotion. He has edited 120 biomedical reference books, particularly in health and 450 papers and chapters. His teaching and research in foods, nutrition and bacterial disease also prepare him to edit this book. He has 4 edited works on nutrition in aging. He has extensive experience working with natural products, alcohol, exercise, functional foods and dietary extracts for health benefits and safety issues, including getting 12 patents. Dr. Watson has done laboratory studies in mice on immune functions that decline with aging and the role of supplements in delaying this process as modified by alcohol and drugs of abuse.


Contributors Preface Foreword Volume One Part I: General Aspects of Alcohol Toxicity, Consumption, and Disease Evolutionary and Historical Aspects of Ethanol Ingestion Alcohol Metabolism: General Aspects Intake of Different Alcoholic Beverages and Life-style and Psychosocial Factors Genetic Aspects of Alcohol Metabolism: An Overview Predictors of Alcohol Consumption Binge Drinking: Patterns, Explanations, and Policy Breath and Blood Alcohol Effects of Food and Body Composition on Blood Alcohol Levels Disposal of Ethanol Carbon Atoms Effect of Alcohol on Water and Sodium Homeostasis Energy from Alcohol The Mediterranean Diet and the Contribution and Role of Alcohol The Role of Alcohol in Injury Deaths Death from Alcohol Poisoning Alcohol and the Workplace Alcohol Misuse in Adolescents: Epidemiology, Clinical Characteristics, Diagnosis, and Treatment Alcohol Misuse in Adolescents: Individual Differences, Prevention, Identification, and Intervention What is the Impact of Alcohol on Learning in University Students? The Relationship Between Alcohol Misuse and the Homelessness Alcohol and Sport Activities: Spectator's Perspective Part II: Damage/Disease General Aspects of Pathology An Overview of Pathologies Occurring in Alcohol Abusers Gender Differences in Alcohol Pathology Psychological Effects of Alcohol Misuse The Effect of Alcohol on Quality of Life Alcohol and Road Accidents Trauma and Alcohol Clinical Implications of Alcohol Misuse for Surgery Fetal Alcohol Spectrum Disorder Nutritional Status in Alcoholics Alcohol and Body Composition Beneficial Components of White Wine Polyphenols and Alcohol: Complementary Mechanisms for the Protective Effects of Moderate Wine Consumption Overview of ALDH Polymorphism: Relation to Cardiovascular Effects of Alcohol Overview on the Effects of Amount and Type of Alcohol on Morbidity and Mortality Alcohol-related Mortality in Russia (ii) Organ Damage Epidemiology and Risk Factors Involved in Alcoholic Liver Disease Polymorphism and Alcoholic Liver Disease Liver Injury During Alcohol Use and Withdrawal Alcohol Consumption and Diabetes Mellitus Alcoholic Ketoacidosis Alcohol, Alcoholism and Effects on the Kidney and Kidney Disease Alcohol Intake and the Lower Urinary Tract Alcohol and Prostate Cancer Oral Health and Alcohol Volume 2 Alcohol and the Gastrointestinal Tract Alcohol, ALDH2 Genotypes and Intestinal Cancer Alcohol and Pancreatitis The Skin and Alcohol Alcohol, Blood Pressure and Hypertension Alcohol and Stroke Alcoholic Cardiomyopathy Epidemiologic Aspects of ALDH2 Genotypes and Cardiovascular Parameters Alcoholic Myopathy: Clinical Aspects Alcohol and the Eye: Friend or Foe Marchiafava-Bignami Disease in Alcoholism Peripheral Neuropathy (iii) Cells, Pathways, Interactions, Processes Defects in Methionine Metabolism: Its Role in Ethanol-induced Liver Injury Roles of Kupffer Cells in Alcoholic Liver Disease The Role of the Stellate Cell in Alcohol Mediated Tissue Injury The Role of T Lymphocytes in the Pathogenesis of Alcoholic Liver Disease Oxidative Stress in Alcoholic Liver Disease: Clinical Studies The Relationship between Alcohol-induced Apoptosis and Oxidative Stress in the Liver Alcohol and HIV Interactions in the Natural History and Treatment of HIV/AIDS Alcohol and Hepatitis Virus Interactions in Liver Pathology Moderate Alcohol and Fibrosis in Chronic Viral Hepatitis Ethanol-Taurine Interactions in the Brain: Mechanisms and Pathophysiological Implications The Effect of Ethanol on Ion Channels in the Brain: A New Look A Nitric Oxide Signaling Pathway Protects the Developing Brain against Alcohol-induced Neuronal Death Signaling Pathways in the Heart and Moderate Alcohol Intake Effects of Alcohol on Vascular Function Vascular and Biochemical Effects of Moderate Alcohol Consumption: Mechanisms of Protection Against Cardiovascular Disease Alcohol and Xenobiotics in Placenta Damage Molecular Mechanisms in Fetal Alcohol Syndrome: Shh-signaling The Process of Bacterial Translocation and Implications for Health in Alcoholics Alcohol, Altered Gut Permeability, and Endotoxins Hormonal Responses in Alcoholism Alcohol-induced Changes in the GH-IGF Axis Mechanisms in Prostate Damage by Alcohol Signaling Pathways in Human Breast Cells in Response to Alcohol: Mechanisms for Alcohol-induced Breast Cancer The Ubiquitin-Proteasome System in Alcohol-Induced Pathology Alcohol and Alkylating Agents DNA Damage Resulting from Alcohol Abuse with Special Reference to the Brain Purine Metabolism and the Influence of Alcoholic Beverages The Role of PKC Isozymes in Mediating Responses to Ethanol Ethanol Modulation of cAMP-dependent Protein Kinase Subunits Activity: Mechanisms and Functional Consequences Adhesion Molecules and Alcohol Consumption Glucose-regulated Stress Proteins (GRPs) and Alcohol Heat Shock Proteins and Alcohol Role of Oxidative Stress in Alcohol-Induced Mitochondrial Dysfunction Alcohol and Apoptosis Volume 3 Alcohol and Fatty Acid Ethyl Esters Modification of Proteins by Reactive Ethanol Metabolites: Adduct Structure, Functional and Pathological Consequences The Effect of Acetaldehyde on Plasma Autoantibodies in Alcohol-related Tissue Diseases Alcohol-induced Membrane Damage Alcohol Abuse and Eating Disorders The Relationship Between Obesity and Alcoholic Pathology Protein Deficiency and Alcohol: Interactions and Organ Effects Tryptophan Metabolism and Alcoholism Part III: Selective Methods Used in Alcohol Research Selective Methods Used in Alcohol Research: Screening in Primary Care - Methods and Approaches Psychometric Assessment of Alcohol Use Self-reported Intake of Alcohol: Methods and Approaches Use of the DSM-IV: Methods and Approaches The Alcohol-related Problems Survey: Developing and Testing a Screening Measure for Older Adults The Rapid Alcohol Problems Screen: Methods and Application Methods for Determining Blood Alcohol Concentration: Current and Retrospective Urinary Markers of Alcohol Consumption Methods for Measuring Genetic Variations in ADH and SLDH Loci: A Practical Approach Histological Localization of Alcohol Dehydrogenase: Methods, Approaches and Applications Assays for Alcohol and Aldehyde Dehydrogenase: Methods, Approaches and Applications Detecting ADH and ALDH Enzymes in Cells and Tissues using Western Blotting Use of Selectively Bred Alcohol-preferring Rats to Study Alcohol Abuse, Relapse and Craving Animal Models of Chronic Alcohol-Induced Liver Damage Acute Ethanol Dosing Regimens: Methods and Approaches Use of Isolated Cells in the Study of Ethanol-Induced Hepatotoxicity Animal Models of Fetal Alcohol Syndrome: Methods and Approaches Genetically Engineered Animals in Alcohol Research cDNA Arrays in Alcohol-Related Pathology: Methods and Approaches Practical Methods for Determining mRNA Levels in Alcohol-Exposed Tissues and Its Application to Experimental Pathology Diagnosis of Fetal Alcohol Syndrome: Measurement of the Facial Dysmorphology Nuclear Magnetic Resonance: Methods and Application to Alcohol Effects in the Liver Index

Product Details

  • ISBN13: 9780125643702
  • Format: Hardback
  • Number Of Pages: 2192
  • ID: 9780125643702
  • weight: 5610
  • ISBN10: 0125643705
  • edition: Special ed.

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