Emerging Topics in Physical Virology is a state-of-the-art account of recent advances in the experimental analysis and modeling of structure, function and dynamics of viruses. It is the first interdisciplinary book that integrates a review of relevant experimental techniques, such as cryo-electron microscopy, atomic force microscopy and mass spectrometry with the latest results on the biophysical and mathematical modeling of viruses. The book comprehensively covers the structure and physical properties of the protein envelopes that encapsulate and hence protect the delicate viral genome, their assembly and disassembly, the organization of the viral genome, infection, evolution, as well as applications of viruses in Biomedical Nanotechnology. It is an essential primer for scientists working in all aspects of virology, including the increasing use of viruses and virus-like particles in bio- and nano-technology. Its review style makes it moreover suitable for non-experts as an introduction into this exciting research area.
Cryo-Electron Microscopy of Viruses; What Does It Take to Make a Virus: The Concept of the Viral SelfA"; New Insights into Viral Architecture via Affine Extended Symmetries; Viral Structure, Function and Dynamics via Mass Spectrometry; Mechanical Properties of Viruses; An Overview of Capsid Assembly Kinetics; Assembly and Disassembly of Deltahedral Viral Shells; What Determines the Size of an RNA Virus?; Physics of Viral Infectivity: Matching Genome length with Capsid Size; Topology of Viral DNA; The Use of Viruses in Biomedical Nanotechnology.