The concept of epigenetics has been known about since the 1940s, but it is only in the last 10 years that research has shown just how wide ranging its effects are. It is now a very widely-used term, but there is still a lot of confusion surrounding what it actually is and does.
Epigenetics is a new textbook that brings together the structure and machinery of epigenetic modification, how epigenetic modification controls cellular functions, and the evidence for the relationship between epigenetics and disease. It is a valuable source of information about all aspects of the subject for undergraduate students, graduate students, and professionals.
Chapter 1. Introduction to the Study of Epigenetics Chapter 2. The Basis of the Transcription Process Chapter 3. DNA Packaging and Chromatin Architecture Chapter 4. Modifying the Structure of Chromatin Chapter 5. DNA Methylation Chapter 6. Post-Translational Modification of Histones Chapter 7. Histone Modification Machinery Chapter 8. Locus-Specific Control of Histone-Modifying Enzyme Action Chapter 9. Epigenetic Control of Cell-Specific Gene Expression Chapter 10. Epigenetic Control of the Mitotic Cell Cycle Chapter 11. The Epigenetic Basis of Gene Imprinting Chapter 12. Epigenetic Control of Cellular Differentiation Chapter 13. Reversibility of Epigenetic Modification Patterns Chapter 14. Epigenetic Predisposition to Disease and Imprinting-Based Disorders Chapter 15. Epigenetics of Memory, Neurodegeneration, and Mental Health Chapter 16. Epigenetics of Cancer