Essential Concepts in Molecular Pathology

Essential Concepts in Molecular Pathology

By: William B. Coleman (editor), Gregory J. Tsongalis (editor)Hardback

Special OrderSpecial Order item not currently available. We'll try and order for you.

Description

This streamlined "essential" version of the Molecular Pathology (2009) textbook extracts key information, illustrations and photographs from the main textbook in the same number and organization of chapters. It is aimed at teaching students in courses where the full textbook is not needed, but the concepts included are desirable (such as graduate students in allied health programs or undergraduates). It is also aimed at students who are enrolled in courses that primarily use a traditional pathology textbook, but need the complementary concepts of molecular pathology (such as medical students). Further, the textbook will be valuable for pathology residents and other postdoctoral fellows who desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school.

About Author

William B. Coleman, PhD is Professor of Pathology and Laboratory Medicine at the University of North Carolina School of Medicine (Chapel Hill, NC), and Director of the UNC Program in Translational Medicine. In addition, he is affiliated with the Curriculum in Toxicology, the Cancer Biology Training Program, and is a member of the UNC Lineberger Comprehensive Cancer Center. Dr. Coleman is actively involved in teaching biomedical graduate students and is a four-time recipient of the Joe W. Grisham Award for Excellence in Graduate Student Teaching from the Molecular and Cellular Pathology graduate students at UNC-Chapel Hill. Dr. Coleman is active in the leadership of the American Society for Investigative Pathology, and is a member of the American Association for Cancer Research. He serves as an associate editor for The American Journal of Pathology, BMC Cancer, and PLoS One, and serves on the editorial boards of Clinica Chimica Acta, Experimental and Molecular Pathology, Archives of Pathology and Laboratory Medicine, Laboratory Investigation, and Current Pathobiology Reports, and has served as an ad hoc reviewer for 95 other journals. Dr. Coleman's major research interests are in the molecular pathogenesis of human cancers, with a specific interest in breast cancer epigenetics, liver carcinogenesis, and lung cancer biology. His research has been funded by the NIH/NCI, The Susan G. Komen Breast Cancer Foundation, Friends for an Earlier Breast Cancer Test, and the UNC Lineberger Comprehensive Cancer Center. Dr. Coleman is the author of over 125 original research articles, reviews, and book chapters. In addition, Dr. Coleman has co-edited or co-authored eight books on topics related to molecular pathology, molecular diagnostics, and the molecular pathogenesis of human cancer. Affiliations and Expertise Professor, Department of Pathology and Laboratory Medicine, Curriculum in Toxicology, UNC Program in Translational Medicine, UNC Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA Greg Tsongalis is the Director of the Laboratory for Clinical Genomics and Advanced Technology (CGAT) at the Dartmouth-Hitchcock Medical Center and Norris Cotton Cancer Center (NCCC) in Lebanon, NH and a Professor of Pathology and Laboratory Medicine at the Audrey and Theodor Geisel School of Medicine at Dartmouth in Hanover, NH. He is a member of the NCCC Molecular Therapeutics Program and the gastrointestinal and breast cancer clinical oncology groups. In 2016 he became a member of Dartmouth College's Program in Experimental and Molecular Medicine (PEMM), and he has served on the advisory board of the Health Care Genetics Professional Science Master's Degree Program at the University of Connecticut (Storrs, CT). His area of expertise is in the development and implementation of clinical molecular diagnostic technologies. His research interests are in the pathogenesis of human cancers, personalized medicine and disruptive technologies. He has authored/edited twelve textbooks in the field of molecular pathology, published more than 200 peer reviewed manuscripts, and has been an invited speaker at both national and international meetings. He has served on numerous committees of the AACC, ASIP, FASEB and AMP where he is a past President. He is active in the Alliance for Clinical Trials in Oncology, the Association for Molecular Pathology, the American Association for Clinical Chemistry, the American Association of Bioanalyts, and the American Society for Investigative Pathology. He serves on the editorial boards of 8 journals including Clinical Chemistry, Experimental and Molecular Pathology, and the Journal of Molecular Diagnostics. He also serves on numerous corporate scientific advisory boards.

Contents

PART I Essential Pathology - Mechanisms of Disease Chapter 1 Cell Injury, Cell Death, and Cellular Adaptation John J. Lemasters, M.D., Ph.D. Chapter 2 Acute and Chronic Inflammation Vladislav Dolgachev, Ph.D. and Nicholas W. Lukacs, Ph.D. Chapter 3 Infection and Host Response Sheldon M. Campbell, M.D., Ph.D. and Margret Oethinger, M.D.,Ph.D. Chapter 4 Neoplasia William B. Coleman, Ph.D., and Tara Rubinas, M.D. PART II Concepts in Molecular Biology and Genetics Chapter 5 Basic Concepts in Human Molecular Genetics W. Edward Highsmith, Ph.D., and Kara A. Mensink, M.S., C.G.C. Chapter 6 The Human Genome: Implications for the Understanding of Human Disease William B. Coleman, Ph.D, Gregory J. Tsongalis, Ph.D. and Ashley Rivenbark, M.D. Chapter 7 The Human Transcriptome: Implications for the Understanding of Human Disease Reinhold Schafer, Ph.D., Matthias E. Futschik, Ph.D., Wolfgang Kemmner, Ph.D., and Christine Sers, Ph.D. Chapter 8 The Human Epigenome: Implications for the Understanding of Human Disease Manel Esteller, Ph.D. and Maria Berdasco, Ph.D. Chapter 9 The Human Proteome: Implications for the Understanding of Human Disease Lance Liotta, Ph.D., Virginia Espina, Claudia Fredolini, Weidong Zhou, and Emanuel Petricoin Chapter 10 Integrative Systems Biology: Implications for the Understanding of Human Disease M. Michael Barmada, Ph.D. and David C. Whitcomb PART III Principles and Practice of Molecular Pathology Chapter 11 Pathology: The Clinical Description of Human Disease William K. Funkhouser, M.D., Ph.D. Chapter 12 Molecular Pathogenesis: The Biological Basis of Human Disease William B. Coleman, Ph.D, and Gregory J. Tsongalis, Ph.D. Chapter 13 Integration of Molecular and Cellular Pathogenesis Jason H. Moore, Ph.D., and C. Harker Rhodes, M.D. PART IV Molecular Pathology of Human Disease Chapter 14 Molecular Basis of Cardiovascular Disease Avrum I. Gotlieb, M.D.C.M. and Amber Chang Liu Chapter 15 Molecular Basis of Hemostatic and Thrombotic Diseases Nigel S. Key, M.D., and Alice Ma, M.D. Chapter 16 Molecular Basis of Lymphoid and Myeloid Diseases Dong-Er Zhang, Ph.D. and Joseph Biggs, Ph.D. Chapter 17 Molecular Basis of Diseases of Immunity David O. Beenhouwer, Ph.D. Chapter 18 Molecular Basis of Pulmonary Disease Dani S. Zander, M.D., and Carol Farver, M.D. Chapter Chapter 19 Molecular Basis of Diseases of the Gastrointestinal Tract Antonio Sepulveda, M.D., Ph.D. and Dara L. Aisner, M.D., Ph.D. Chapter 20 Molecular Basis of Liver Disease Satdarshan P. Singh Monga, M.D. and Jaideep Behari, M.D. Chapter 21 Molecular Basis of Diseases of the Exocrine Pancreas Markus M. Lerch, M.D. Chapter 22 Molecular Basis of Diseases of the Endocrine System Malcolm M. Martin, M.D., Arlene L. Martin, M.D., Alan L.Y. Pang, Ph.D., and Wai-Yee Chan, Ph.D. Chapter 23 Molecular Basis of Gynecologic Diseases Samuel Chi-ho Mok, Ph.D., Kwong-Kwok Wong, Ph.D., Karen Lu, M.D., Karl Munger, Ph.D., and Zoltan Nagymanyoki, Ph.D. Chapter 24 Molecular Pathogenesis of Diseases of the Kidney Amy K. Mottl, M.D., M.P.H., and Carla Nester, M.D., M.S.A. Chapter 25 Molecular Basis of Prostate Disease William G. Nelson, M.D., Ph.D., Angelo M. De Marzo, M.D., Ph.D., and Carlise R. Bethel, M.D., Ph.D. Chapter 26 Molecular Basis of Breast Disease Christos Sotiriou, M.D., Ph.D., Natasha Snoj, Phuong Dinh, and Philippe Bedard Translational Research Unit, Jules Bordet Institute, Universite Libre de Bruxelles, Brussels, Belgium Chapter 27 Molecular Basis of Skin Disease John A. McGrath, Ph.D., and Vesarat Wessagowit, M.D., Ph.D. Chapter 28 Molecular Basis of Diseases of the Nervous System Joshua A. Sonnen, M.D., C. Dirk Keene, M.D., Robert F. Hevner, M.D., and Thomas J. Montine, M.D., Ph.D. PART V Practice of Molecular Medicine Chapter 29 Molecular Diagnosis of Human Disease Grant Bullock, M.D., Ph.D., and Lawrence M. Silverman, Ph.D. Chapter 30 Molecular Assessment of Human Disease in the Clinical Laboratory Gregory J. Tsongalis, Ph.D. and Joel A. Lefferts, M.D. Chapter 31 Pharmacogenomics and Personalized Medicine in the Treatment of Human Disease Gregory J. Tsongalis, Ph.D. and Hong Kee Lee, Ph.D.

Product Details

  • ISBN13: 9780123744180
  • Format: Hardback
  • Number Of Pages: 462
  • ID: 9780123744180
  • weight: 1550
  • ISBN10: 0123744180

Delivery Information

  • Saver Delivery: Yes
  • 1st Class Delivery: Yes
  • Courier Delivery: Yes
  • Store Delivery: Yes

Prices are for internet purchases only. Prices and availability in WHSmith Stores may vary significantly

Close