It is estimated that 1.5 million infants undergo surgery and anesthesia in the USA each year. However, there are serious concerns within the pediatric anesthesia community regarding the safety of anaesthesia in infants and children. There is mounting evidence from animal studies that anesthetics in common clinical use are neurotoxic to the developing brain and cause long-term neurobehavioral abnormalities. Essentials of Anesthesia for Infants and Neonates provides a comprehensive guide to the special needs of infants undergoing anesthesia. It focuses on the first year of life, the time when anesthesia mortality and morbidity is highest. Chapters are illustrated in color throughout, and include sections on newborn physiology for anesthetic management, specific procedures, pain management, and topics such as regional anesthesia and sedation. Written by nationally recognized experts, this book will become an invaluable point of reference for any physician interested in pain management in the first year of life.
Mary Ellen McCann is an Associate Professor at Harvard Medical School and a Senior Associate in Pediatric Anesthesia at Boston Children's Hospital. She did her pediatric and anesthesia training at Massachusetts General Hospital and completed her M.P.H, at the Harvard School of Public Health in 2005. She served on the board for the Society for Pediatric Anesthesia, and is a Principal Investigator for the GAS trial along with Andrew Davidson of Australia. The focus of her research is the safety of general anesthesia and sedatives with regard to neurodevelopmental outcomes of human infants and toddlers. Christine Greco is an Assistant Professor at Harvard Medical School and a Senior Associate in Pediatric Anesthesia at Boston Children's Hospital. She completed her pediatric training at Ohio State University and anesthesia training at the University of California, San Francisco. She is clinical director of the pain service at Boston Children's Hospital where she created the first accredited fellowship training program in pediatric pain medicine. Kai Matthes practices pediatric anesthesia in Wailuku, Hawaii. Having obtained his medical degree and Ph.D. from the University of Erlangen in Germany, anesthesiology residencies at Beth Israel Deaconess Medical Center and Harvard Medical School led to the positions of attending anesthesiologist and Associate Professor at Harvard Medical School. Dr Matthes has a broad research background in the field of anesthesiology, gastrointestinal endoscopy and minimally invasive surgery.
List of contributors; Preface; Part I. Newborn Physiology for Anesthetic Management: 1. The term infant Mary Ellen McCann; 2. The preterm infant Lauren R. Kelly Ugarte and Thomas J. Mancuso; 3. Origin of the NICU Amy Vinson; 4. Hemodynamics in the infant Viviane Nasr; 5. Measures of carbon dioxide Larry Rhien; 6. Glucose control Monica Hoagland; 7. Oxygen management Augusta Sola; 8. Temperature control Laura Downey; 9. Neonatal resuscitation Monica Kleinman; 10. Congenital abnormalities and syndromes Anne Lynn and Katherine Gentry; 11. Myopathies of the newborn Phil Morgan and Vincent Hsieh; Part II. Newborn Anesthesia: 12. Preoperative preparation Lynne Ferrari; 13. Developmental pharmacology: the neonate Cynthia Tung and Robert Holzman; 14. The newborn airway Sim Jagannathan and Shivani S. Patel; 15. Fluid and transfusion management Justin Long, Tiffany Frazee and Hubert Benzon; 16. Neonatal ventilation strategies Gerhard Wolf; 17. Anesthetic induced neurotoxicity Sulpicio Soriano and Dusica Bajic; 18. New anesthetic agents on the horizon Kai Matthes and Thomas Weissmueller; 19. Monitoring of the newborn and infant under anesthesia Michael King, Samuel Rodriguez and Kathleen Chen; Part III. Specific Newborn and Infant Procedures: 20. Anesthesia for neurosurgical procedures Roby Sebastian and Craig McClain; 21. Anesthesia for otolarygologic procedures in infants and neonates Richard Anderson, Anthony Anderson and Charles Nargozian; 22. Anesthesia for plastic surgery Petra Meier-Haran; 23. Anesthesia for abdominal wall reconstruction procedures Ellen Choi and Sam Wald; 24. Anesthesia for intraabdominal procedures Raymond Park and Edmund Cooper; 25. Anesthesia for urologic surgery Myron Yaster, Deepa Kattail and Jessica A George; 26. Anesthesia for thoracic surgery Cornelius Sullivan; 27. Congenital diaphragmatic hernia Elizabeth Eastburn and Bridget Muldowney; 28. Congenital heart disease in the neonate and infant cardiac catheterization and cardiac surgery Kirsten Odegard and Morgan Brown; 29. Non-cardiac surgery in neonates with cardiac disease Annette Schure; 30. Neonatal and infant tumors Laura Leduc; 31. Anesthesia for transplant surgery Evan Burke and Franklyn Cladis; 32. Anesthesia for interventional radiology procedures Mary Landrigan-Ossar; 33. Anesthesia for conjoined twins Lynne Maxwell and Phil Bailey; 34. Anesthesia for fetal surgery Linda Bulich, Arielle Mizrahi and Kha Tran; Part IV. Pain Management and other Newborn Anaesthesia Concerns: 35. Pain management in neonates Christine Greco and Charles Berde; 36. Regional anesthesia in neonates and infants Karen Boretsky; 37. Procedural sedation Mary Ellen McCann and Christine Greco; 38. Ambulatory anesthesia in infants Sharon Redd and Ethan Sanford; 39. Apnea and bradycardia Sam Rodriguez; 40. Neonatal outcomes Joseph Cravero; 41. Research on newborns and infants Patcharee Sriswasdi; Index.