Charles Brenton Huggins won the Nobel prize in 1966 for his extensive work in cancer research. He has spent fifty years at the laboratory bench exploring the nature of this disease in an attempt to understand and control it. In this volume, based almost exclusively on experiments conducted over the past twenty years at the University of Chicago, is both the record of Huggins's own research and, in Huggins's words, "a do-it-yourself guide for cancer research workers." Written simply and clearly so that the experiments can be easily reproduced, the book presents Huggins's experiments in the induction of breast cancer and leukemia in rodents. It also describes the methods he discovered to prevent cancer and to cure many of the cancers he has been able to induce. Although most of the material concerns breast cancer and leukemia, research on other kinds of tumors is also described.
Charles Brenton Huggins has been a member of the faculty of the University of Chicago since 1927. From 1951 to 1969 he was director of the Ben May Laboratory for Cancer Research and he has been the William B. Ogden Distinguished Service Professor since 1962. In 1966 he won the Nobel prize in Medicine and Physiology for his work on carcinoma of the prostate.