Interest in the application of nanotechnology to medicine has surged in recent years and could transform the way we diagnose, treat and prevent diseases such as cancer. However, the clinical success of nanomedicine is limited because of problems with toxicity and therapeutic efficacy. To overcome this it is essential to produce new nanosystems with specific functions, which can be achieved by designing new polymers with particular properties that can be used for nanomedicine. Functional Polymers for Nanomedicine provides a complete overview of the different strategies for designing polymers for nanomedicine applications. The first part of the book looks at the current problems and direction in nanomedicine including a review of current design and targeting of nanocarriers. The second part explores the design of polymers with different functions including hyperbranched polymers, polymersomes, polysaccharides, polymeric micelles and zwitterionic polymers and their applications in gene therapy and drug delivery. This timely book is edited by a leading scientist in nanomedicine and provides a suitable introduction and reference source for advanced undergraduates, postgraduates and academic and industrial researchers in polymer science, nanotechnology and pharmacy interested in materials for medical applications.
Youqing Shen is Qiushi Chair Professor, NSFC Distinguished Young Scholar and Director of Center for Bionanoengineering (CBNE) at Zhejiang University, China and Adjunct Professor, Department of Chemical and Petroleum Engineering, University of Wyoming, USA. His research interests include polymer reaction engineering, biomaterials, drug delivery, gene delivery, cancer chemotherapy and nanotechnologies.
Targeted Drug Delivery in Oncology: Current Paradigm and Challenges; Targeted Nanomedicine: Challenge and Opportunities; Rational Design of Translational Nanocarriers; Functional Polymers for Gene Delivery; Functional Hyperbranched Polymers for Drug and Gene Delivery; Functional Polymersomes for Controlled Drug Delivery; Polymeric Micelle-Based Nanomedicine for siRNA Delivery; Polysaccharide/polynucleotide complexes for cell-specific DNA delivery; Design of complex micelles for drug delivery; Zwitterionic Polymers for Targeted Drug Delivery; Polymer-based Prodrugs for Cancer Chemotherapy; Non-viral vector recombinant mesenchymal stem cells: a promising targeted-delivery vehicle in cancer gene therapy; Near-Critical Micellization for Nanomedicine: Enhanced Drug Loading, Reduced Burst Release;