This acclaimed textbook has been updated to incorporate the many advances in genomics, protein engineering, computational biology and bioinformatics. In the Second Edition, the authors continue to explain evolutionary change at the molecular level in a way that can be understood without much prerequisite knowledge of molecular biology, evolution or mathematics.
DAN GRAUR, Tel Aviv University WEN-HSIUNG LI, University of Chicago
Introduction.- Genes, Genetic Codes, and Mutation.- Dynamics of Genes in Populations.- Evolutionary Change in Nucleotide Sequences.- Rates and Patterns of Nucleotide Substitution.- Molecular Phylogenetics.- Gene Duplication, Exon Shuffling, and Concerted Evolution.- Evolution by Transposition.- Genome Evolution.- Appendix I. Timetables of Evolution.- Appendix II. Basics of Probability.- Literature Cited.- Subject Index.- Appendix I: Spatial and Temporal Frameworks of the Evolutionary Process.- Appendix II: Basics of Probability.- Literature Cited.- Index.- Taxonomic Index.