G Protein-Coupled Receptors: Emerging Paradigms in Activation, Signaling and Regulation Part A: Volume 338 (International Review of Cell and Molecular

G Protein-Coupled Receptors: Emerging Paradigms in Activation, Signaling and Regulation Part A: Volume 338 (International Review of Cell and Molecular

By: Arun K. Shukla (volume_editor)Hardback

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Description

G Protein-Coupled Receptors: Emerging Paradigms in Activation, Signaling and Regulation, Part A, Volume 337 in the International Review of Cell and Molecular Biology series, reviews and details current advances in cell and molecular biology. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. This new release includes comprehensive sections on the classical paradigms of GCPR signaling and regulation, the family of small GTPases: Beyond heterotrimeric G proteins, GPCR endocytosis: Arrestins, arrestin-like proteins, signaling from internalized G Protein-Coupled Receptors, GPCR kinases, and more.

About Author

Dr. Arun K. Shukla obtained his M.Sc. (Master in Science) from the Center for Biotechnology at the Jawaharlal Nehru University in New Delhi, India. Dr. Shukla did his Ph.D. from the Department of Molecular Membrane Biology at the Max Planck Institute of Biophysics in Frankfurt, Germany. His Ph.D. research work was focused on structural studies of G Protein-Coupled Receptors (GPCRs). Dr. Shukla subsequently carried out his post-doctoral work in the Department of Medicine at the Duke University in North Carolina, USA. During his post-doctoral research work, Dr. Shukla focused on understanding the biophysical and structural basis of ss-arrestin mediated regulation of GPCRs and non-canonical GPCR signaling. Dr. Shukla has served as an Assistant Professor in the Department of Medicine at the Duke University in Durham, North Carolina, USA.Dr. Shukla is currently an Assistant Professor in Department of Biological Sciences and Bioengineering at the Indian Institute of Technology, Kanpur, India. Dr. Shukla is also an Intermediate Fellow of the Wellcome Trust-DBT India Alliance. The research program in Dr. Shukla's laboratory is focused on understanding the molecular mechanism of activation, signaling and regulation of G Protein-Coupled Receptors.

Contents

1. Classical Paradigms of GCPR signaling and regulation 2. The family of small GTPases: Beyond heterotrimeric G proteins 3. GPCR endocytosis: Arrestins, arrestin-like proteins and beyond 4. Signaling from internalized G Protein-Coupled Receptors 5. GPCR kinases: Something old, something new 6. Ubiquitination of GPCRs: Roles in endocytosis and receptor turnover 7. RAMPs: Discovery and future perspective 8. Cross-talk between GPCRs and RTKs: Novel signaling platforms 9. "Regulator of G protein signaling" protein family: Fine-tuning and emerging paradigms 10. GCPR-interacting lipids: Structural, functional and signaling implications

Product Details

  • ISBN13: 9780128137727
  • Format: Hardback
  • Number Of Pages: 182
  • ID: 9780128137727
  • weight: 450
  • ISBN10: 012813772X

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