The manner in which genetic research associated with addiction is conducted, interpreted and translated into clinical practice and policy initiatives raises important social, ethical and legal issues. Genetic Research on Addiction fulfils two key aims; the first is to identify the ethical issues and requirements arising when carrying out genetically-based addiction research, and the second is to explore the ethical, legal and public policy implications of interpreting, translating and applying this research. The book describes research guidelines on human protection issues such as improving the informed consent process, protecting privacy, responsibilities to minors and determining whether to accept industry funding. The broader public health policy implications of the research are explored and guidelines offered for developing effective social interventions. Highly relevant for clinicians, researchers, academics and policy-makers in the fields of addiction, mental health and public policy.
Audrey R. Chapman is Healey Professor of Medical Ethics and Humanities, Department of Community Medicine and Health Care, University of Connecticut School of Medicine, Farmington, CT, USA.
Abstracts; Part I. Introduction: 1. Introduction to volume Audrey R. Chapman; 2. The implications of genetic research on alcohol dependence for prevention and treatment Rebecca Mathews, Adrian Carter and Wayne Hall; 3. Promises and risks for participants in studies of genetic risk for alcohol or drug dependence Carl Erik Fisher, Deborah Hasin and Paul Appelbaum; Part II. Research Ethics: 4. Improving the informed consent process in research with substance abusing participants David S. Festinger and Karen L. Dugosh; 5. Ethical responsibilities to minor children with drug abusing parents in research trials Thomas McMahon; 6. Protecting privacy in genetic research on alcoholism and other addictions Mark A. Rothstein; 7. Uses and limitations of certificates of confidentiality for protecting research on addiction Zita Lazzarini; 8. Ethical issues in genomic databases and biobanks involving human subjects David B. Resnik; 9. Should addiction researchers accept funding derived from the profits of addictive consumptions? Peter J. Adams; 10. Ethical issues related to alcohol research funding from the alcohol beverage industry Thomas Babor; Part III. Translating Addiction Research: 11. The public health implications of genetic research on addiction Rebecca Mathews, Wayne Hall and Adrian Carter; 12. Genetics, addiction, and stigma Jo C. Phelan and Bruce G. Link; 13. Lay beliefs about genetic influences on alcoholism: implications for prevention and treatment Toby Jayaratne, Alicia Giordimaina and Amy Gaviglio; 14. Personalizing risk: how behavioral genetics research into addiction makes the political personal Jonathan M. Kaplan; Part IV. Conclusions: 15. Conclusions and guidelines for conducting and translating research on alcohol dependence and addiction Audrey R. Chapman, Jonathan M. Kaplan and Adrian Carter; Index.