Genetics: From Genes to Genomes (6th edition)

Genetics: From Genes to Genomes (6th edition)

By: Leland Hartwell (author), Leroy Hood (author), Janice Fischer (author), Michael Goldberg (author)Hardback

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Description

Genetics: From Genes to Genomes is a cutting-edge, introductory genetics text authored by an unparalleled author team, including Nobel Prize winner, Leland Hartwell. This edition continues to build upon the integration of Mendelian and molecular principles, providing students with the links between the early understanding of genetics and the new molecular discoveries that have changed the way the field of genetics is viewed.

About Author

Dr. Michael Goldberg is a professor at Cornell University, where he teaches introductorygenetics and human genetics. He was an undergraduate at Yale Universityand received his Ph.D. in biochemistry from Stanford University. Dr. Goldberg performedpostdoctoral research at the Biozentrum of the University of Basel (Switzerland)and at Harvard University, and he received an NIH Fogarty Senior InternationalFellowship for study at Imperial College (England) and fellowships from theFondazione Cenci Bolognetti for sabbatical work at the University of Rome (Italy).His current research uses the tools of Drosophila genetics and the biochemical analysisof frog egg cell extracts to investigate the mechanisms that ensure proper cellcycle progression and chromosome segregation during mitosis and meiosis. Dr. Leland Hartwell is President and Director of Seattles Fred Hutchinson CancerResearch Center and Professor of Genome Sciences at the University of Washington.Dr. Hartwells primary research contributions were in identifying genes that controlcell division in yeast, including those necessary for the division process as well asthose necessary for the fi delity of genome reproduction. Subsequently, many of thesesame genes have been found to control cell division in humans and oft en to be thesite of alteration in cancer cells.Dr. Hartwell is a member of the National Academy of Sciences and has receivedthe Albert Lasker Basic Medical Research Award, the Gairdner FoundationInternational Award, the Genetics Society Medal, and the 2001 Nobel Prize inPhysiology or Medicine. Dr. Hood received an MD from the Johns Hopkins Medical Schooland a PhD in Biochemistry from the California Institute of Technology. His research interests include immunology, development and the development of biological instrumentation (e.g. the protein sequenator and the automated fluorescent DNA sequencer). His research played a key role in unraveling the mysteries of anitbody diversity. Dr. Hood has taught molecular evolution, immunology, molecular biology and biochemistry. he is currently the Chairman (and founder) of the cross-disciplinary Department of Molecular Biotechnology at the University of Washington. Dr. Hood has received a variety of awards including the Albert Lasker Award for Medical Research (1987), Dickson Price (1987), Cefas Award for Biochemistry (1989), and the Distinguished Service Award from the national Association of Teachers (1998). He is deeply involved in K-12 science educatiohn. His hobbies include running, mountain climbing, and reading. Dr. Janice Fischer is a Professor at The University of Texas at Austin, where she is an award-winning teacher of genetics and Director of the Biology Instructional Office. She received her Ph.D. in biochemistry and molecular biology from Harvard University, and did postdoctoral research at The University of California at Berkeley and The Whitehead Institute at MIT. In her current research, Dr. Fischer uses Drosophila to examine the roles of ubiquitin and endocytosis in cell signaling during development.

Contents

1. Genetics: The Study of Biological Information2. Mendel's Principles of Heredity3. Extensions to Mendel's Laws4. The Chromosome Theory of Inheritance5. Linkage, Recombination, and the Mapping of Genes on Chromosomes6. DNA Structure, Replication, and Recombination7. Anatomy and Function of a Gene: Dissection Through Mutation8. Gene Expression: The Flow of Information from DNA to RNA to Protein9. Digital Analysis of Genomes10. Genome Annotation11. Analyzing Genomic Variation12. The Eukaryotic Chromosome13.Chromosomal Rearrangements and Changes in Chromosome Number 14. Bacterial Genetics15. Organellar Inheritance16. Gene Regulation in Prokaryotes17. Gene Regulation in Eukaryotes18. Manipulating the Genomes of Eukaryotes19. The Genetic Analysis of Development20. The Genetics of Cancer 21. Variation and Selection in Populations22. Genetics of Complex Traits

Product Details

  • ISBN13: 9781259700903
  • Format: Hardback
  • Number Of Pages: 848
  • ID: 9781259700903
  • weight: 1780
  • ISBN10: 1259700909
  • edition: 6th edition

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