Genomic and Precision Medicine: Foundations, Translation, and Implementation (3rd edition)

Genomic and Precision Medicine: Foundations, Translation, and Implementation (3rd edition)

By: Huntington F. Willard (editor), Geoffrey S. Ginsburg (editor)Hardback

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Description

Genomic and Precision Medicine: Foundations, Translation, and Implementation highlights the various points along the continuum from health to disease where genomic information is impacting clinical decision-making and leading to more personalization of health care. The book pinpoints the challenges, barriers, and solutions that have been, or are being, brought forward to enable translation of genome based technologies into health care. A variety of infrastructure (data systems and EMRs), policy (regulatory, reimbursement, privacy), and research (comparative effectiveness research, learning health system approaches) strategies are also discussed. Readers will find this volume to be an invaluable resource for the translational genomics and implementation science that is required to fully realize personalized health care.

About Author

Dr. Ginsburg is the founding Director of the Center for Applied Genomics & Precision Medicine in the Duke Institute for Genome Sciences & Policy. He is also Professor of Medicine and of Pathology at Duke University Medical Center, Professor of Biomedical Engineering at Duke Pratt School of Engineering, and Co-Director of the Duke Translational Medicine Institute. Huntington Willard is on the faculty of the Department of Human Genetics at the University of Chicago. Prior to this appointment, Willard was the President and Director of the Marine Biological Laboratory and Professor of Human Genetics at the University of Chicago. He was previously on the faculty at Duke University, where he was founding director of the university-wide Duke Institute for Genome Sciences & Policy from 2003 to 2014, the Nanaline H. Duke Professor of Genome Sciences, and the Arts & Sciences Professor of Biology & Genome Sciences.

Contents

1. Application of Human Genome Information to Clinical Practice 2. Translating genome information into clinical practice and human health 3. Big Data and Translational Bioinformatics Genomic and Personalized Medicine 4. Designing Genome-Based Clinical Studies 5. Developing the Evidence to Support Clinical Use Genomic Biomarkers as Diagnostics 6. Health Risk Assessment and Family History 7. Clinical Decision Support 8. Implementation Science and Integration into Healthcare Systems 9. Pharmacogenetics and Pharmacogenomics 10. Drug Repurposing and Repositioning 11. Point of Care Devices 12. Overview of Policy, Ethical and Social Considerations 13. Educational Issues and Strategies for Genomic Medicine 14. Regulation of Genomic Technologies 15. Economic Value of Genomic Medicine 16. Reimbursement 17. Impact of Patents on Genomic Medicine

Product Details

  • ISBN13: 9780128006818
  • Format: Hardback
  • Number Of Pages: 398
  • ID: 9780128006818
  • weight: 770
  • ISBN10: 0128006811
  • edition: 3rd edition

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