In "Problem Solving in Haematology", an expert panel lead readers through real-life clinical presentations on how to diagnose and manage a variety of clinical cases seen in haematology practice. The problem-based learning approach should have an immediate impact as a teaching tool to trainees, and more experienced clinicians will find the literature summaries useful to keep them up-to-date with the latest clinical trials and current thinking in the field.Over 30 common and challenging clinical scenarios create a foundation incorpoarting recent medical literature and presenting the latest guidelines for management. Each case opens with a series of questions which is a useful testing exercise for readers. This is followed by background information on the disorder, recent developments in the field and a conclusion on management. Algorithms reflecting the strategic steps in management are included wherever possible. The case-approach lends itself to quick and easy reading, whilst also offering invaluable information on diagnosis and management from experienced authors.
Abbreviation; Introduction; Part I: Work up; 1. Approach to the patient with an abnormal blood count; Part II: Haemostasis and thrombosis; 2. Anticoagulation; 3. Bleeding in an ITU patient; 4. Easy bruising; 5. Inherited disorders of coagulation; 6. Thrombophilia; Part III: Red cell disorders and aplastic anaemia; 7. The investigation of anaemia and the anaemia of chronic disease; 8. Aplastic anaemia; 9. Paroxysmal Nocturnal Haemaglobinuria (PNH); 10. Haemaglobinopathy case 1 - Sickle cell disease; 11. Haemaglobinopathy case 2 - Thalassaemia major; Part IV: Blood transfusion; 12. Complications of transfusion case 1 - acute haemolytic transfusion reaction (ABO incompatibility); 13. Massive blood transfusion; 14. Platelet alloimunisation; 15. Complications of transfusion case 2 - TRALI; Part V: Acute and chronic leukaemia, and myelodysplasia; 16. Acute myeloid leukaemia (AML); 17. Paediatric acute lymphoblastic leukaemia (ALL); 18. Adult acute lymphoblastic leukaemia (ALL); 19. Chronic lymphocytic leukaemia (CLL) case 1 - early stage disease; 20. Chronic lymphocytic leukaemia (CLL) case 2 - advanced stage disease; 21. Chronic myeloid leukaemia; 22. Low risk myelodysplastic syndrome (MDS); Part VI: Myeloproliferative disorders; 23. Primary polycythaemia; 24. Chronic idiopathic myelofibrosis (CIMF); 25. Essential thrombocythaemia; 26. Hypereosinophilic syndrome; Part VII: Lymphoma; 27. Hodgkin lymphoma case 1 - early stage disease; 28. Hodgkin lymphoma case 2 - advanced stage disease; 29. High grade (diffuse large B cell; DLBCL) non-Hodgkin's lymphoma (NHL); 30. Primary central nervous system lymphoma (PCNSL); 31. Indolent lymphoma case 1 - follicular non-Hodgkin lymphoma (NHL); 32. Indolent lymphoma case 2 - Waldenstrom's macroglobulinaemia; Part VIII: Myeloma; 33. Myeloma case 1 - diagnosis and prognosis; 34. Myeloma case 2 - management; 35. Myeloma case 3 - treatment in the less fit patient; 36. Myeloma case 4 - solitary plasmacytoma; 37. Myeloma case 5 - AL amyloid; General index.