Discusses advances in antibody engineering and recognition of small molecules. Focuses on new basic and applied science in hapten and assay chemistry and formats. Explores developing methods that improve sensitivity, allow real-time repeated analyses and multi-analyte analysis. Provides data validation guidelines and quality standards for immunoassay methods. Includes an introductory chapter by Bruce D. Hammock and Shirley J. Gee.
Impact of Emerging Technologies on Immunochemical Methods for Environmental Analysis ; Recombinant Antibodies Against Haptenic Mycotoxins ; Sequence Analysis of Individual Chains of Antibodies to Triazine Herbicides ; Recombinant Antibodies to Diuron: A Model for the Phenylurea Combining Site ; Antidioxin Monoclonal Antibodies: Molecular Modeling of Cross-Reactive Congeners and the Antibody Combining Site ; Antibody Mimics Obtained by Noncovalent Molecular Imprinting ; Type Reactivity for Analyte Profiling ; Analytical Representation and Prediction of Macroscopic Properties: A General Interaction Properties Function ; Strategies for Immunoassay Hapten Design ; Hapten Versus Competitor Design Strategies for Immunoassay Development ; Miniaturized Microspot Multianalyte Immunoassay Systems ; Very Sensitive Antigen Detection by Immuno-Polymerase Chain Reaction ; Self-Regenerating Fiber-Optic Sensors ; Fiber-Optic Immunosensors for Detection of Pesticides ; Liposome-Amplified Immunoanalysis for Pesticides ; Polarization Fluoroimmunoassay for Rapid, Specific Detection of Pesticides ; Immunoaffinity Chromatography Applications in Pesticide Metabolism and Residue Analysis ; Development of Assay for Analysis of Hg^2]+ Based on Sulfur-Containing Ligands ; Interpretation of Immunoassay Data ; Guidelines to the Validation and Use of Immunochemical Methods for Generating Data in Support of Pesticide Registration ; Quality Standards for Immunoassay Kits ; Immunochemical Approach for Pesticide Waste Treatment Monitoring of s-Triazines ; Evaluation and Application of Immunochemical Methods for Mycotoxins in Food ; Immunodetection of Ecosystem Contaminants: Research, Application, and Acceptance in Canada