Covering the latest technologies in process engineering, this handbook and ready reference features high pressure processing, alternative solvents and processes, extraction technologies and biotransformations -- describing greener, more efficient and sustainable techniques. The result is an expert account of engineering details from lab-scale experiments to large-scale industrial design. The major focus is on the engineering aspects of extraction with organic and supercritical solvents, ionic liquids or surfactant solutions, and is supplemented by aspects of both up- and downstream processing, biotransformation, as well as a survey of typical products in food, pharmaceutical and cosmetic applications. This is rounded off by market developments, economic considerations and regulations requirements in the field Authored by experts from leading industrial and academic institutions, this is essential reading for the hands-on scientist and office manager alike.
Prof. Hans-Jorg Bart is the Head of the Department Process Engineering at Technical University of Kaiserslautern, Germany. He obtained his academic degrees from Technical University of Graz, Austria, and later became Head of the Christian Doppler Laboratorium "Modelling of Reactive Systems in Process Engineering". Professor Bart has authored over 300 publications, is on the editorial board of several journals, including "Chemical Engineering Technology Journal" and "CIT-Plus". Prof. Bart is Head of the ProcessNet working party "Extraction" and is an appointed board member of several scientific working parties. Dr. Stephan Pilz is former Head of the High Pressure Technologies Development at Evonik Degussa GmbH in Trostberg, Germany and furthermore developed processes for natural substances. After passing functions in Business Development and Strategic Projects, he is now in International Sales and located in Shanghai. He received his degree from Stuttgart University, Germany, worked on his master thesis with British Gas, UK, and his PhD with Daimler Chrysler AG at Karlsruhe University. Dr. Pilz is co-chairman of the Process-Net working party "Natural Plant Extracts - Processes and Products".
Preface EXTRACTION OF NATURAL PRODUCTS FROM PLANTS - AN INTRODUCTION Introduction Cultivation Extraction Extraction Techniques Purification SOLUBILITY OF COMPLEX NATURAL AND PHARMACEUTICAL SUBSTANCES Introduction Solubility Calculations Thermodynamic Modeling Examples Summary ALTERNATIVE SOLVENTS IN PLANT EXTRACTION Introduction Ionic Liquids in the Extraction of Natural Compounds from Plant and Fungi Surfactants and Aqueous Two-Phase Systems in Plant Extraction Summary HIGH PRESSURE PROCESSING Introduction Supercritical Fluids Physical Properties - Mass Transfer Characteristics Process Units Process Design and Operation Applications PROCESS ENGINEERING AND MINI-PLANT TECHNOLOGY Introduction Chromatographic Screening Preparative Task Liquid-Liquid Extraction Mini-Plant Technology for Extraction Process Development Cost Estimation Total Process Development Future Developments EXTRACTION TECHNOLOGY Introduction Extraction Process Basics Experimental Procedures Theoretical Modeling and Scale-Up Industrial Extraction Equipment EXTRACTION OF LIGNOCELLULOSE AND ALGAE FOR THE PRODUCTION OF BULK AND FINE CHEMICALS Introduction Products from Lignocellulose Polysaccharides and Sporopollenin from Marine Algae NATURAL PRODUCTS - MARKET DEVELOPMENT AND POTENTIALS Introduction Natural Products Market Overview Natural Products in Food and Functional Food Natural Products for Pharmaceutical Applications Summary REGULATIONS AND REQUIREMENTS Introduction Definition of Plant Extracts as Medicines or Foods - A Borderline Issue Application of Plant Extracts in Flavorings, Functional Foods, Novel Foods and Food Supplements Requirements Concerning Quality and Safety Issues Conclusions