This volume features contributions from both researchers and clinicians on innate inflammation in the central nervous system. The focus of the volume is on molecular and cellular mechanisms that are altered by innate inflammation and the translation to cerebrovascular risk. Also included are examinations of animal studies reflecting the pathophysiological consequences following acute or chronic ischemia with the reference to time course and level of innate inflammation as well as formation of reactive oxygen species of different kind. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.