Atrial fibrillation is underdiagnosed and preventative strategies are underutilized. The disease is estimated to rise to an epidemic level, increasing by over 50 per cent by the end of the decade, occurring commonly in the setting of otherwise 'healthy' aging. "Innovative Management of Atrial Fibrillation" provides a forum for a full discussion on this topical matter.Distinguished experts from both electrophysiology and cardiac surgery place their work in the context of future development, examining the short-comings of current pharmacological treatments. This results in a unique, comprehensive review for cardiologists, cardiac surgeons and anyone who wishes to gain a complete perspective on the fast-paced field of atrial fibrillation. The material ranges from atrial pathophysiology to advanced minimally invasive surgical ablation and cutting edge palliative and curative therapeutic options. The book also includes the examination of innovative management strategies and the next generation of therapies, giving an essential insight into the emerging potential of gene therapy.
List of Contributors. Preface. Part I. On the Atrial Substrate. Chapter 1. Electrophysiologic Basis of Atrial Fibrillation. Chapter 2. Neurological Basis of Atrial Fibrillation. Chapter 3. Mechanical Basis of Atrial Fibrillation. Chapter 4. Molecular Basis of Atrial Fibrillation. Chapter 5. Atrial Plasticity. Part II. Developing Strategies for AF Management. Chapter 6. AV Node Ablation. Chapter 7. Percutaneous Atrial Catheter Ablation. Chapter 8. Implantable Device Therapy. Chapter 9. Surgical Ablation Therapy I. Maze Procedure. Chapter 10. Surgical Ablation Therapy II. Endocardium-Based Catheter Ablation. Chapter 11. Surgical Ablation Therapy III. Epicardium-Based Catheter Ablation. Chapter 12. Modification of the Left Atrial Appendage. Part III. Potential Areas of Opportunity for AF Management. Chapter 13. Transpericardial Therapy. Chapter 14. Gene Therapy. Chapter 15. Tissue Engineering. Index
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