This book takes an in depth and hard look at the current status and future direction of treatment predictive markers in Personalized Medicine for the brain from the perspectives of the researchers on the cutting edge and those involved in healthcare implementation. The contents provide a comprehensive text suitable as both a pithy introduction to and a clear summary of the "science to solutions" continuum in this developing field of Personalized Medicine and Integrative Neuroscience. The science includes both measures of genes using whole genome approaches and SNIPS as well as BRAINmarkers of direct brain function such as brain imaging, biophysical changes and objective cognitive and behavioral measurements. Personalized Medicine for Brain Disorders will soon be a reality using the comprehensive quantitative and standardized approaches to genomics, BRAINmarkers and cognitive function. Each chapter provides a review of recent relevant literature; show the solutions achieved through integrative neuroscience and applications in patient care thus providing a practical guide to the reader.
The timeliness of this book's content is propitious providing bottom line information to educate practicing clinicians, health care workers and researchers, and also a pathway for undergraduate and graduates interested in further their understanding of and involvement in tailored personal solutions.
Dr. Stephen H. Koslow has been an innovator and creative leader in the fields of psychopharmacology, neuroscience and informatics. He has joined efforts in all these fields by now helping to catalyze Personalized Medicine into a reality. He continues to run his own consulting company, and his efforts in Neuroinformatics, and special interest in the clinical areas of mental illness. He had worked for many years at the National Institutes of Mental Health (NIH) where he had a major leadership role in these same areas. Dr. Evian Gordon is Adjunct Associate Professor of Psychiatry at Sydney Medical School, University of Sydney. He is also the founding Director of the Brain Dynamic Centre (BDC), and heads BDC's Integrative Neuroscience Program. He is also the CEO of Brain Resource, a publicly listed biotech Company, which developed out of BDC in 2001, and is now the industry affiliate of BDC. He is a pioneer of 'intergrative neuroscience' and has over 25 years in bringing together complementary human brain imaging technologies. With his experience he has established the first fully standardized international database on the human brain, under the auspices of Brain Resource. He has over 350 peer-reviewed publications and has produced a 14-part television series on models of the human brain.