Laboratory Diagnosis in Neurology

Laboratory Diagnosis in Neurology

By: Hansotto Reiber (author), Brigitte Wildemann (author), Patrick Oschmann (author)Hardback

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Up-to-date, comprehensive, and beautifully illustrated, Laboratory Diagnosis in Neurology presents all the measuring parameters and methods relevant to the analysis of cerebrospinal fluid, serum, and tissues affected by neurologic disease and syndromes. Following an introduction to basic concepts, the book guides clinicians through the methods of CSF analysis, neurochemical examinations, clinical applications of neuroimmunology, microbiology and virology, neurogenetic tests, and evaluation of biopsies. Readers will learn about the equipment and various procedures, and how to effectively differentiate similar methods. In the final section of the book, the authors provide a systematic introduction to the pathophysiology and laboratory findings for specific clinical disorders, indications for particular test methods, and criteria for diagnostic interpretation. Key features: Clear presentation of pearls, pitfalls, and practical tips in blue boxes for at-a-glance review Contributions by neurologists, psychiatrists with experience in laboratory analysis, clinical chemists, and neurochemists More than 140 high-quality illustrations, mostly in full color, demonstrating common findings Appendix with basic rules for interpreting disease-specific patterns, recommendations for quality control, and a list of the most important reference values An indispensable tool for neurologists, laboratory physicians, and pathologists, this book is also a valuable reference for neurosurgeons, internists, and psychiatrists.

About Author

Professor, CSF and Complexity Studies, University of Goettingen, Goettingen, Germany


Basics 1 The Cerebrospinal Flud - Its Production and Circulation in the Subarachnoid Space 2 Blood-Brain Barrier and Blood-CSF Barrier Function The Blood-Brain Barrier The Blood-CSF Barrier Function 3 Dynamics of Serum and Brain Proteins in the CSF and Blood Serum Proteins in the CSF Brain Proteins in the CSF Brain Proteins in the Blood Analysis 4 Basic Methods of Analysis Immunochemistry and Immune Complex Analysis Qualitative Electrophoretic Methods of Detection with or without Immunodetection Immunohistochemistry 5 Cerebrospinal Fluid Analysis Cerebrospinal Puncture Measurement of Cerebrospinal Fluid Pressure Cytodiagnosis Proteins Lactate and Glucose Diagnosis of Pathogens Markers of Dementia and Neuronal Destruction 6 Serum Analysis General Serum Analysis Special Serum Analysis 7 Autoantibodies and Antineural Antibodies Autoantibodies Antineural Antibodies 8 Neurogenetics Basics Monogenic Neurological Diseases Polygenic or Multifactorial Neurological Diseases 9 Biopsy Brain Biopsy Nerve Biopsy Muscle Biopsy Clinical Pictures 10 Inflammation and Autoimmune Diseases Inflammation Caused by Pathogens Inflammation not Caused by Pathogens (Autoimmune Diseases) 11 Dementia and Psychiatric Disorders Alzheimer's Disease Lewy Body Dementia Frontotemporal Lobar Degeneration Multiple System Atrophy Subcortical Atherosclerotic Encephalopathy Creutzfeldt-Jacob Disease Psychiatric Disorders 12 Cerebral Ischemia and Hemorrhage Ischemic Cerebral Infarction Intracerebral Hemorrhage Subarachnoid Hemorrhage Cerebral Hypoxia 13 Polyneuropathy 14 Pseudotumor Cerebri, Ventricular Drainage, and Neurosurgery Pseudotumor Cerebri External Ventricular Drainage, Ventriculoarterial and Ventriculoperitoneal Shunts Cerebrospinal Fluid Rhinorrhea and Otorrhea 15 Epileptic Seizures 16 Brain Tumors Primary Brain Tumors Secondary Brain Tumors Malignant Non-Hodgkin Lymphoma, Leukemia, and Meningeosis blastomatosa 17 Metabolic Disorders Mitochondrial Diseases Lysosomal Diseases Peroxisomal Diseases Cerebrotendinous Xanthomatosis (CTX) Leukodystrophy / Leukocephalopathy in Organic Aciduria Diseases of Copper Metabolism Specialized Laboratories 18 Parasitosis and Tropical Diseases Appendix 19 CSF Reports Goettingen CSF Report Procedure of CSF Analysis Evaluation Interpretation 20 Quality Control of Protein Analysis Special Features of CSF Analysis Quality Control of Individual Parameters Quality Control of CSF Cytodiagnosis 21 Reference Ranges of Analytes in CSF and Serum Electrolytes and Substrates Proteins Amino Acids, Lipids, and Vitamins Cells Index

Product Details

  • ISBN13: 9783131441010
  • Format: Hardback
  • Number Of Pages: 292
  • ID: 9783131441010
  • weight: 1091
  • ISBN10: 3131441011
  • translations: German
  • language of text: English

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  • Saver Delivery: Yes
  • 1st Class Delivery: Yes
  • Courier Delivery: Yes
  • Store Delivery: Yes

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