Landmark Experiments in Molecular Biology critically considers breakthrough experiments that have constituted major turning points in the birth and evolution of molecular biology. These experiments laid the foundations to molecular biology by uncovering the major players in the machinery of inheritance and biological information handling such as DNA, RNA, ribosomes, and proteins. Landmark Experiments in Molecular Biology combines an historical survey of the development of ideas, theories, and profiles of leading scientists with detailed scientific and technical analysis.
Department of Biochemistry, Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, POB 9649, Bat Galim, Haifa, 31096, Israel
CHAPTER 1: Introduction CHAPTER 2: Prehistory of Molecular Biology: 1847-1944 CHAPTER 3: Avery Identifies DNA as the Genetic Material CHAPTER 4: Hershey and Chase Clinch the Role of DNA as the Genetic Material CHAPTER 5: Watson and Crick Solve the Structure of DNA CHAPTER 6: Meselson and Stahl Demonstrate that DNA is Replicated Semiconservatively CHAPTER 7: Defining the Genetic Code CHAPTER 8: The Adaptor Hypothesis and the Isolation of transfer RNA CHAPTER 9: The Discovery and Rediscovery of messenger RNA CHAPTER 10: Deciphering the Genetic Code CHAPTER 11: The Surprising Discovery of Split Genes and RNA Splicing Chapter 12: Epilogue, Theory-driven versus experiment-directed discoveries in molecular biology