Efficient computer programs have made it possible to elucidate and analyze large-scale genomic sequences. Fundamental tasks, such as the assembly of numerous whole-genome shotgun fragments, the alignment of complementary DNA sequences with a long genome, and the design of gene-specific primers or oligomers, require efficient algorithms and state-of-the-art implementation techniques. This textbook emphasizes basic software implementation techniques for processing large-scale genome sequences and provides executable sample programs.
Simple String Search Algorithms; Sorting; Lookup Tables; Suffix Arrays; Space-Efficient String Search; Approximate String Search Algorithms; Seeded Alignment; Highly-Specific Oligomer Design; Whole Genome Shotgun Sequencing.
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- ID: 9781860946356
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