The present understanding of the various implications of lectins in pathology are summarised in this timely text. With contributions from leading investigators in the field of lectin research, Lectins and Pathology provides up-to-date information on key developments within this field, including the use of lectins and lectin-binding molecules as tools, the involvement of endogenous (animal or human) lectins in inflammation, cancer invasion and metastasis, as well as the importance of lectins in bacteriology and parasitology.
This volume contains useful knowledge for clinical investigators, cell biologists, biochemists and biotechnologists, as well as for the graduate students interested in getting a comprehensive coverage of this field.
1. Lectins and Pathology : An Overview 2. Carrier-immobilized Carbohydrate Ligands: Design of the Lectin-detecting Tools and their Applications with Focus on Histopathology 3. Lectins, Microglia and Alzheimer's Disease 4. The Role of Galectin-3 in Inflammation 5. The Role of Galectin-3 in Tumor Metastasis 6. Laminin-binding Lectins during Cancer Invasion and Metastasis 7. Lectins as Diagnostic Tools and Endogenous Targets in AIDS and Prion Diseases 8. Protein-carbohydrate Interactions in the Attachment of Enterotoxigenic Escherichia Coli to the Intestinal Mucosa 9. Lectin-carbohydrate Interactions in Bacterial Pathogenesis 10. Lectin-Mediated Interaction of Parasites with Host Cells