Long-Term Potentiation: v. 3 - A Debate of Current Issues (Bradford Books)

Long-Term Potentiation: v. 3 - A Debate of Current Issues (Bradford Books)

By: Michel Baudry (editor), Joel L. Davis (editor)Hardback

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This is the third volume in a series of books devoted to the mechanisms and functional significance of two forms of synaptic plasticity, Long-Term Potentiation (LTP) and Long-Term Depression (LTD), which are widely assumed to play critical roles in information processing and storage in the brain. Long-Term Potentiation offers the most recent hypotheses concerning the molecular and cellular mechanisms underlying LTP and LTD, discusses the functional significance of LTP and LTD in neuronal networks, and reviews several examples of network simulations incorporating LTP- and LTD-like rules of synaptic modification.The book is organized into several sections covering different aspects of the field ranging from molecular and cellular processes to network models. The often deliberately controversial contributions are from the leading laboratories in the field and reflect contemporary multidisciplinary approaches.

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About Author

Michel Baudry is Associate Professor in the Department of Biology at the University of Southern California. Joel L. Davis is Program Officer, Cognitive, Neural, and Biomolecular Science and Technology Division, Office of Naval Research.


Part 1 Molecular and cellular processes in synaptic plasticity: mGluR1 and mGluR5 glutamate receptors - molecular biology, pharmacology and roles on hippocampal synaptic transmission, Joel Bockaert et al; AMPA-glutamate receptor regulation and synaptic plasticity, Steve Standley et al; the expression of LTP of glutamate receptor-mediated synaptic transmission as determined by the redox state of NMDA receptors and the extent of NMDA receptor activation during a tetanus, June C. Hirsch et al; analysis of synaptic plasticity and memory in the mammalian brain with the gene-knockout technology, Chong Chen and Susumu Tonegawa. Part 2 LTP and LTD mechanisms: involvement of AMPA receptors in LTP mechanisms and memory, John Larson and Peter W. Vanderklish; mechanisms of homosynaptic LTD in the hippocampus, Robert C. Malenka; homosynaptic LTD and depotentiation in the hippocampus in vivo, Serge Laroche et al; LTP and LTD in the visual cortex, Alfredo Kirkwood and Mark F. Bear; electroresponsive properties of cerebellar purkinje cells in mGlur1 gene-lacking mice, Francis Crepel et al; LTD and LTP at the corticostriatal synapse, Antonio Pisani et al. Part 3 Synaptic plasticity in network processes: generation of temporal correlations in firing of pyramidal cells by networks of inhibitory neurons, Roger D. Traub et al; LTP and LTD and the encoding of memory in small ensembles of hippocampal neurons, Robert E. Hampson and Sam A. Deadwyler; the constraint of synaptic potentiation and memory formation by entorhinal-hippocampal network dynamics, James J. Chrobak and Gyorgy Buzsaki; network determinants of hippocampal synaptic plasticity, Theodore W. Berger et al. Part 4 Synaptic plasticity in network models: what LTP, LTD and cortical receptive fields tell us about synaptic modification, Harel Shouval and Leon M. Cooper; linking LTP to network function - a simulation of episodic memory in the hippocampal formation, Michael E. Hasselmo and Chantal E. Stern; adaptive stimulus representations in a computational model of cortical-hippocampal function, Mark A. Gluck and Catherine E. Myers; adapting recurrent cortical excitation, Christof Koch et al.

Product Details

  • publication date: 03/01/1997
  • ISBN13: 9780262024099
  • Format: Hardback
  • Number Of Pages: 448
  • ID: 9780262024099
  • weight: 1021
  • ISBN10: 0262024098

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