Looking Inside the Disordered Mind

Looking Inside the Disordered Mind

By: Ahmad Hariri (author)Paperback

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About Author

Ahmad Hariri is Professor of Psychology and Neuroscience at Duke University, where he is also Director of the Laboratory of NeuroGenetics. After completing his B.S. and M.S. in evolutionary biology at the University of Maryland, Dr. Hariri completed his doctorate through the UCLA Interdepartmental Ph.D. Program for Neuroscience with Dr. Susan Bookheimer. He next completed a postdoctoral fellowship at the National Institute of Mental Health with Dr. Daniel Weinberger. From 2003-2009, he was first Assistant and then Associate Professor in the Departments of Psychiatry and Psychology at the University of Pittsburgh. In 2009, Dr. Hariri received the APA Distinguished Scientific Award for Early Career Contribution to Psychology. Earlier this year he was named a Highly Cited Researcher by Thomson Reuters, identifying him as 1 of only 129 investigators whose research is amongst the top 1% most cited in the field of Neuroscience and Behavior.


Chapter 1. Getting Inside and Getting Around Circuit concepts and approach BOLD basics Neuroanatomical planes and directional terms UNIT 1. THE CORTICOLIMBIC CIRCUIT FOR RECOGNITION AND REACTION Chapter 2. The Corticolimbic Circuit: Anatomy Circuit hub: Amygdala (basolateral complex, central nucleus, and intercalated cell masses) Interconnected circuitry: thalamus, sensory association cortex, hypothalamus, brainstem, substantia innominata (bed nucleus of the stria terminalis and nucleus basalis of meynert), insula, hippocampal formation, prefrontal cortex Basic information flow supporting recognition and reaction Chapter 3. The Corticolimbic Circuit: Order Fear learning: Conditioning, extinction, recall Faces and facial expressions: threat, ambiguity, uncertainty, novelty Anxiety Chapter 4. The Corticolimbic Circuit: Disorder Amygdala hyper/hypoactivity and circuit imbalance Exaggerated and dysregulated responses to threat Symptoms including depression, mania, anxiety, phobia, aggression, and abnormal social interactions UNIT 2. THE CORTICOSTRIATAL CIRCUIT FOR MOTIVATION AND ACTION Chapter 5. The Corticostriatal Circuit: Anatomy Circuit hub: Ventral striatum (nucleus accumbens) Interconnected circuitry: thalamus, amygdala, ventral pallidum, dorsal striatum, dorsal pallidum, prefrontal cortex, midbrain (substantia nigra and ventral tegmental area) Basic information flow supporting motivation and action Chapter 6. The Corticostriatal Circuit: Order Reward learning: classical and instrumental conditioning Goal-directed behavior Primary and secondary reinforcers Impulsivity Chapter 7. The Corticostriatal Circuit: Disorder Ventral striatum hyper/hypoactivity and circuit imbalance Abnormal and dysregulated motivations and goal-directed behaviors Symptoms including anhedonia, mania, hyperactivity, aggression, addiction, body image distortion, overeating UNIT 3. THE CORTICOHIPPOCAMPAL CIRCUIT FOR MEMORY AND EXECUTIVE CONTROL Chapter 8. The Corticohippocampal Circuit: Anatomy Circuit hub: Dorsolateral prefrontal cortex Interconnected circuitry: Hippocampal formation (hippocampus, entorhinal cortex, perirhinal cortex, parahippocampal cortex), neocortical association areas, midbrain Basic information flow supporting memory and executive control Chapter 9. The Corticohippocampal Circuit: Order Long-term memory: The librarian and the library Executive control: Working memory, attention and response selection Focus and performance Chapter 10. The Corticohippocampal Circuit: Disorder Hippocampal formation dysfunction: deficits in encoding and recall of long-term memories Symptoms including retrograde and anterograde amnesia, mild cognitive impairment, and delusions Dorsolateral prefrontal cortex dysfunction: dysregulation of other circuits, disorganized thinking, remembering, and planning Symptoms including poor emotion regulation, impulse control, inattention, obsessions and compulsions, and disintegration of thought and executive control Glossary

Product Details

  • publication date: 27/01/2015
  • ISBN13: 9780878939794
  • Format: Paperback
  • Number Of Pages: 220
  • ID: 9780878939794
  • weight: 880
  • ISBN10: 0878939792

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