Matrix Metalloproteinases In The Central Nervous System

Matrix Metalloproteinases In The Central Nervous System

By: Katherine Conant (editor), Paul E. Gottschall (editor)Hardback

Up to 2 WeeksUsually despatched within 2 weeks

Description

This book presents the reader with an understanding of the role played by matrix metalloproteinases (MMPs) in the normal and diseased central nervous system (CNS). These enzymes may be important to brain development, and may also contribute to tissue destruction, which is observed with inflammatory and degenerative conditions of the brain. The book provides a background on the biology of MMPs, and on the stimuli and conditions that are linked to an increase in their production and activity. It describes the targets of MMPs, which include matrix proteins such as collagen, soluble cytokines and chemokines, and cell surface receptors. Studies implicating MMPs in neuronal process outgrowth and cell migration in CNS development are covered. The book also touches on studies suggesting that, in certain situations, dysregulated MMP activity and/or production may be critical to blood-brain barrier breakdown and neuronal damage.

Contents

# A Brief Overview # Regulation of MMP Expression # MMP Function # MMPs and TIMPs in Development # MMPs and TIMPs in Disease

Product Details

  • ISBN13: 9781860945595
  • Format: Hardback
  • Number Of Pages: 348
  • ID: 9781860945595
  • ISBN10: 1860945597

Delivery Information

  • Saver Delivery: Yes
  • 1st Class Delivery: Yes
  • Courier Delivery: Yes
  • Store Delivery: Yes

Prices are for internet purchases only. Prices and availability in WHSmith Stores may vary significantly

Close