Modern NMR Approaches to the Structure Elucidation of Natural Products: Volume 1: Instrumentation and Software

Modern NMR Approaches to the Structure Elucidation of Natural Products: Volume 1: Instrumentation and Software

By: G. E. Martin (editor), David Rovnyak (editor), Antony Williams (editor), Clemens Anklin (contributor), Roberto Gil (contributor), Mark O'Neill Johnson (contributor), Zhong Zhong (contributor), Kruppa Kruppa (contributor), Thomas Williamson (contributor), William Reynolds (contributor)Hardback

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Description

Aimed at Academic researchers, Industrialists and Postgraduates. The following may be interested in buying the book: The American Society of Pharmocognosy: http://www.phcog.org/ Association of Managers of Magnetic Resonance Labs: http://www.ammrl.org/ NMR Discussion Group: http://www.nmrdg.org.uk/ Society for Applied Spectroscopy http://www.s-a-s.org/home/ This text will appeal to those working in the structure elucidation of natural products as it brings together a diverse but relevant selection of topics. It covers both methodology and application to specific disciplines within natural product chemistry.

About Author

Antony J. Williams graduated with a BSc and PhD in chemistry from the University of Liverpool and University of London respectively. He subsequently became a Post-doctoral Fellow at the National Research Council in Ottawa and then an NMR Facility Director at the University of Ottawa. He has also worked as an NMR Technology Leader at Eastman-Kodak Company in Rochester and held a number of positions, including Chief Science Officer, at ACD/Labs. In 2007, he established ChemZoo, Inc and became host of ChemSpider, one of the primary internet portals for chemistry. ChemSpider was acquired by the Royal Society of Chemistry (RSC) in 2009 and Dr Williams is currently Vice-President of Strategic Development at the RSC. He presently holds an adjunct position at UNC-Chapel Hill and has been a member of the ACS since 1996. Gary E. Martin graduated with a BS in Pharmacy in 1972 from the University of Pittsburgh and a PhD in Pharmaceutical Sciences from the University of Kentucky in 1975, specializing in NMR spectroscopy. He was a Professor at the University of Houston from 1975 to 1989, assuming the position of Section Head responsible for US NMR spectroscopy at Burroughs Wellcome, Co. in Research Triangle Park, NC, eventually being promoted to the level of Principal Scientist. In 1996 he assumed a position at what was initially the Upjohn Company in Kalamazoo, MI and held several positions there through 2006 by which time he was a Senior Fellow at what was then Pfizer, Inc. In 2006 he assumed a position as a Distinguished Fellow at Schering-Plough responsible for the creation of the Rapid Structure Characterization Laboratory. He is presently a Distinguished Fellow at Merck Research Laboratories. David Rovnyak earned his BS from the University of Richmond, and his PhD studying high resolution NMR of quadrupolar nuclei at MIT. He transitioned to solution phase biomolecular NMR in postdoctoral work at the Harvard Medical School before joining the Chemistry Department at Bucknell University, where he has been recognized with Bucknell's Excellence in Teaching Award. He currently serves as Assistant Editor of Concepts in Magnetic Resonance. His lab pursues interdisciplinary topics in biophysical research including bile acid aggregation, methods in protein NMR, nonuniform sampling and small molecule profiling.

Contents

An introduction to Modern NMR Spectroscopy for the Elucidation of Natural Products;NMR Magnets, a Historical Overview;Small volume NMR - Microprobes and Nanoprobes;Cryogenically Cooled NMR Probes: A Revolution for NMR Spectroscopy;Application of LC-NMR to the study of natural products;Application of non-uniform sampling for sensitivity enhancement of small molecule heteronuclear correlation NMR spectra;NMR Spectroscopy using Several Parallel Receivers;Dereplication using H1 NMR;Application of Computer Assisted Structure Elucidation;Multidimensional Spin Correlations by Covariance NMR;Future Approaches For Data Processing;Nutriceuticals;Molecular structure identification by atomic force microscopy

Product Details

  • ISBN13: 9781849733830
  • Format: Hardback
  • Number Of Pages: 329
  • ID: 9781849733830
  • weight: 674
  • ISBN10: 184973383X

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