The two volumes "Science of Synthesis: Multicomponent Reactions" critically
review the state of the art of domino, sequential, and consecutive
multicomponent reactions in what is a highly dynamic field. They serve as the
basis for practical application to reach the goals of diversity-oriented
synthesis, reaction design, and novel synthetic concepts.
The following topics are covered: Biginelli Reaction, Strecker Reaction,
Hantzsch Pyridine Synthesis, Mannich Reaction, Petasis Reaction,
Willgerodt-Kindler Reaction, Kabachnik-Fields Reaction, Passerini Reaction, Ugi
Reaction, Gewald Reaction (Vol. 1); Michael Additions, Wittig Reactions,
Cycloadditions, Reactions Involving an a,ss-Unsaturated Carbonyl Compound as
Electrophilic Component with Electron-Deficient Alkynes as Electrophiles,
Reactions with Cycloaddition as the Key Step, Boron-Mediated Multicomponent
Reactions, Silicon-Mediated Multicomponent Reactions, Free-Radical Mediated
Multicomponent Reactions, Metal-Mediated Multicomponent Reactions (Vol.