Muscle Biopsy: A Practical Approach: Expert Consult; Online and Print (4th Revised edition)

Muscle Biopsy: A Practical Approach: Expert Consult; Online and Print (4th Revised edition)

By: Caroline A. Sewry (author), Anders Oldfors (author), Victor Dubowitz (author)Hardback

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2014 BMA Medical Book Awards Highly Commended in Pathology category! Muscle Biopsy: A Practical Approach gives you all of the unparalleled guidance necessary to effectively interpret and diagnose muscle biopsy specimens for the full range of diseases in both adults and children. Authored by Dr. Victor Dubowitz, an internationally renowned figure in the field of muscle disease, this medical reference book takes an integrated approach to diagnosis and assessment of muscle biopsies that includes clinical, genetic, biochemical, and pathological features. It's the comprehensive, up-to-date coverage you need to evaluate muscle disorders with confidence. "Overall, this is a well written and comprehensive textbook of muscle pathology that will be of invaluable assistance to laboratories reporting muscle pathology" Reviewed by The Bulletin of The Royal College of Pathologists, Jan 2015 Bridge the gap between clinical syndromes/disorders and their underlying pathologies with the guidance of muscle disease expert, Dr. Victor Dubowitz, who skillfully guides you through the complexities of pathologic diagnoses and their implications for clinical treatment. Understand and apply expert techniques for obtaining a muscle biopsy, and familiarize yourself with the histochemical, histological, electron microscopical, and molecular appearance of normal muscle and the pathology of individual muscle disease. Read the entire contents and download all of the images online at Expert Consult. Apply all of the latest diagnostic techniques for neurodegenerative and genetic diseases with a brand-new chapter on myopathies associated with systemic disorders and aging, and use advanced techniques such as immunohistochemistry and immunoblotting to produce the most accurate diagnoses possible for a full range of muscle disorders. Stay current in practice with state-of-the-art coverage of genetic markers for individual conditions and antibodies used in immunocytochemical diagnosis. Understand the genetics of muscular dystrophies with absolute clarity through the use of brilliantly simple diagrams and tables, and compare your specimens to a wealth of superb color images capturing the full spectrum of muscle biopsy findings. Take advantage of international insights and fresh perspectives in muscle diseases and disorders from new author Dr. Anders Oldfors, from the Department of Pathology, University of Goteborg, Sweden.


Section 1 The Biopsy: Normal and Diseased Muscle 1. The procedure of muscle biopsy 2. Histological and histochemical stains and reactions 3. Normal muscle 4. Definition of pathological changes seen in muscle biopsies 5. Ultrastructural changes in diseased muscle 6. Immunohistochemistry 7. How to read a biopsy Section 2 Pathological Muscle: Individual Diseases 8. Classification of neuromuscular disorders 9. Neurogenic disorders 10. Muscular dystrophies and allied disorders I: Duchenne and Becker muscular dystrophy 11. Muscular dystrophies and allied disorders II: limb-girdle muscular dystrophies 12. Muscular dystrophies and allied disorders III: congenital muscular dystrophies 13. Muscular dystrophies and allied disorders IV: Emeryf{Driefuss muscular dystrophies and Bethlem myopathy 14. Muscular dystrophies and allied disorders V: facioscapulohumeral dystrophy, myotonic dystrophy, oculopharyngeal muscular dystrophy 15. Congenital myopathies 16. Myofibrillar myopathies 17. Metabolic myopathies I: glycogenoses 18. Metabolic myopathies II: lipid related disorders and mitochondrial myopathies 19. Endocrine disorders 20. Ion channel disorders 21. Myasthenic syndromes 22. Inflammatory myopathies 23. Toxic and drug-induced myopathies Russell Lane, Charing Cross Hospital Appendix 1. Glossary of commonly used terms References Index

Product Details

  • ISBN13: 9780702043406
  • Format: Hardback
  • Number Of Pages: 592
  • ID: 9780702043406
  • ISBN10: 0702043400
  • edition: 4th Revised edition

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