This volume examines the state-of-the-art in our understanding of the aging brain through the application of brain imaging techniques of neuroscience to the geriatric population. By exploring the neurobiological aspects of geriatric mental health, scientists can begin to understand why abnormal aging happens and what can be done to treat it. Researchers in the fields of geriatric psychiatry, cognitive neuropsychology, neurology, neuroradiology, and physics have combined their expertise to present this accessible, compact review of the field. The chapter authors discuss the use of image modalities and what they can tell us about the aging brain; and present cutting-edge information on image processing and data analysis in the context of geriatric populations. With this book, both novice and seasoned investigators can gain fresh, new insight into geriatric mental health. Key topics: The use of MRI (magnetic resonance imaging), MRS (magnetic resonance spectroscopy), and other modalities with geriatric populations; The application of SPECT (single photon emission computed tomography) and PET (positron emission tomography) to geriatric mental health; Structural brain changes associated with normal aging; Functional neuroanatomy of aging and cognition; Brain structural and functional correlates of Alzheimer's; dementia and mild cognitive impairment; Neuroimaging in late-life schizophrenia
Dr. Aizentstein is an assistant professor of psychiatry at the University of Pittsburgh Medical School and Director of its Geriatric Psychiatry Neuroimaging Laboratory. He received a joint M.D./Ph.D. in medicine and computer science from the University of Illinois, Urbana-Champaign in 1995. Dr. Aizenstein is specialty certified in psychiatry and geriatric psychiatry by the American Board of Psychiatry and Neurology and is a licensed M.D. in the State of Pennsylvania. His main area of research, which has been funded by the National Institute of Mental Health and the National Institute on Aging, is depression later life. In 2004, he was awarded a ""Young Investigators"" grant by the National Alliance for Research on Schizophrenia and Depression for his work on the physiological basis of cognitive impairment in the depressed elderly.
I Introduction; II. Imaging Modalities; III Image Processing; IV Aging; V Affective Disorders; VI Cognitive Disorders; VII Psychotic Disorders; VIII New Imaging Modalities.