Oogenesis - the process by which female germ cells develop intomature eggs, or ova - is a complex process involving many importantelements of developmental and cellular biology: from cell-cellinteractions, complex signalling cascades, specialized cell cyclesand cytoskeleton organization. Oocytes from various species(including clam, starfish, xenopus and mouse) are excellent modelsystems to study the biochemistry of cell division with importantimplications for basic and clinical research. This book describes the entire process of oogenesis inchronological order with contributions from leading internationalresearchers and chapters covering medical and ethicalconsiderations in oogenic biology. Topics include sex determinationand gonadal development, control of meiotic chromosome pairing andhomologous recombination, control of meiotic divisions and theremodelling of the oocyte into a totipotent zygote as well asmedically-assisted reproduction. This volume is an essential resource for all students,researchers and clinicians in developmental and reproductivebiology. Key features: * Reaches beyond the study of simply meiosis to cover all aspectsof oogenesis * Synthesizes recent advances in the field, drawing on studiesfrom different model species * Chapter sequence designed to follow the time line invivo * Written by an international panel of expert researchers
About the Author
MARIE-HELENE VERLHAC, CNRS/Universite Pierre et Marie Curie, Paris, France. ANNE VILLENEUVE, School of Medicine, Stanford University, USA.
- Contributor: Marie-Helene Verlhac
- Imprint: John Wiley & Sons Inc
- ISBN13: 9780470696828
- Number of Pages: 516
- Packaged Dimensions: 175x251x34mm
- Packaged Weight: 1036
- Format: Hardback
- Publisher: John Wiley & Sons Inc
- Release Date: 2010-03-19
- Binding: Hardback
- Biography: MARIE-HELENE VERLHAC, CNRS/Universite Pierre et Marie Curie, Paris, France. ANNE VILLENEUVE, School of Medicine, Stanford University, USA.
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