Heart failure is epidemic throughout the world. A growing incidence and prevalence has resulted in a large population of individuals transitioning to advanced stages of the syndrome and requiring uniquely specialised therapies and cardiac transplantation. Oxford Textbook of Advanced Heart Failure and Cardiac Transplantation is a focused and comprehensive work covering this new and rapidly growing cardiovascular subspecialty. Authored by eminent international experts, it is the authoritative text on advanced heart failure and a central resource for clinicians caring for patients with this conditition. By covering a range of characteristics, therapeutic challenges and practical aspects of managing patients this book provides an in-depth source for cardiologists and other related clinicians. A strong focus on the difficult decision making needed to handle advanced heart failure cases, along with specific knowledge of epidemiology, biology and pathophysiology, creates a key tool for optimally managing these complex patients.
Michael Domanski is a Professor of Medicine at University Health Network, Peter Munk Cardiovascular Centre and the University of Toronto. He is also the Director of Heart Failure Research and the Patient Inpatient Heart Failure Program and Chairman of the Cardiovascular Clinical Trials Oversight Committee. Professor Domanski has previously held director positions at Trinity Medical Centre, North Dakota and Washington Adventist Hospital. Mandeep Mehra is Professor of Medicine and Head of Cardiology at University of Maryland School of Medicine. He is also the Editor-in-Chief of The Journal of Heart and Lung Transplantation. Professor Mehra has previously been affiliated with Louisiana State University and was the Chief of Ochsner Clinic Foundation's Cardiomyopathy and Heart Transplantation Centre. Marc Alan Pfeffer is a Senior Physician at Brigham and Women's Children Hospial, Boston, Massachusetts and Director of their Cardiovascular Grand Rounds program. He is a recipient of the American Heart Association Clinical Research Prize and is a Senior Associate Editor at Circulation. Professor Pfeffer previously held a position as a Professor of Medicine at Harvard Medical School.
Foreword ; 1. Advanced heart failure in perspective ; 2. Cell biology of heart failure ; 3. Physiology and hemodynamic assessment of the failing heart: Current knowledge and unmet needs for advanced heart failure ; 4. Transplantation immunology ; 5. Implantable devices for cardiovascular monitoring ; 6. Endomyocardial biopsy in the failing heart ; 7. Imaging in advanced heart failure ; 8. Pharmologic management of advanced heart failure ; 9. Arrhythmias in heart failure: The AV node and above ; 10. Ventricular Arrhythmias in Heart Failure ; 11. Cardiac Resynchronization ; 12. Advanced heart failure in valvular heart disease ; 13. High risk heart failure surgery: strategies for coronary artery bypass grafting and valve surgery in patients with reduced ejection fraction ; 14. Mechanical circulatory support: patient selection, optimization and inpatient management of the LVAD patient ; 15. Mechanical circulatory support: outpatient management ; 16. Cardiac transplantation overview ; 17. Immunosuppression strategies ; 18. Rejection surveillance, type and treatment ; 19. Complications after cardiac transplantation ; 20. Right heart failure: Anatomy physiology and patho-biology ; 21. Right ventricular failure: Clinical features and management ; 22. Pulmonary arterial hypertension ; 23. End of life care in advanced heart failure ; 24. Future directions in advanced heart failure