Pharmaceutical Aspects of Oligonucleotides

Pharmaceutical Aspects of Oligonucleotides

By: Patrick Couvreur (editor), Claude Malvy (editor)Hardback

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Description

Oligonucleotides diffuse poorly through biological barriers, including cell membranes. They are also rapidly degraded in vivo by nucleuses. Aiming to improve the administration of compounds, the book studies the development of nucleotide chemistry.

Contents

1. Mechanisms of Action of Antisense Oligonucleotides D.M. Tidd and R.V. Giles 2. Chemistry of Oligonucleotides J.W. Engels and E. Uhlmann 3. The Oligonucleotide Prodrug Approach: The Pro-oligonucleotides F. Morvan, J.-J. Vasseur, E. Vives, B. Rayner and J.-L. Imbach 4. Peptide Nucleic Acids P.E. Nielsen 5. Peptide-mediated Delivery of Oligonucleotides E. Vives and B. Lebleu 6. Polymeric Nanoparticles and Microparticles as Carriers for Antisense Oligonucleotides E. Fattal and P.

Product Details

  • ISBN13: 9780748408412
  • Format: Hardback
  • Number Of Pages: 336
  • ID: 9780748408412
  • weight: 871
  • ISBN10: 074840841X

Delivery Information

  • Saver Delivery: Yes
  • 1st Class Delivery: Yes
  • Courier Delivery: Yes
  • Store Delivery: Yes

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