Pharmacology Condensed, 2nd Edition is a companion volume to Rang et al's Pharmacology, sets out to provide the reader with the quintessence of pharmacology, delineating, in text and summary diagrams, the key points of the information which will be needed later in professional life. It will help reinforce the facts and concepts in pharmacology that are essential in appreciating how drugs work and their underlying pathophysiological processes. Each of the 49 short chapters adopts a standard approach and the book includes many illustrations specially designed to summarise textual material. Within each chapter, several drugs may be mentioned but only the most important drugs from each group are set out in bold type. Readers using this book will gain a fuller understanding of the essential aspects of pharmacology. It will also be of considerable help in preparing for examinations. This book is best used with Rang Pharmacology but can also be used in conjunction with another pharmacology textbook.
1 General Principles of drug action 2 Molecular aspects of drug action 3 Excitable tissues and secretory mechanisms 4 Cell proliferation and apoptosis 5 Measurement of drug action 6 Absorption and distribution of drugs 7 Drug metabolism and excretion 8 Pharmacokinetic aspects of drug action 9 The autonomic nervous system 10 Cholinergic transmission 11 Noradrenergic transmission 12 Other peripheral mediators: 5-hydroxytryptamine and purines 13 Other peripheral mediators: peptides and proteins 14 Other peripheral mediators: nitric oxide 15 Cannabinoids 16 Inflammation & anti-inflammatory drugs 17 Immune responses and immunosuppressant drugs 18 Cardiac rhythm and dysrhythmias 19 Blood pressure and hypertension 20 Cardiac blood flow, angina and myocardial infarction 21 Cardiac output and cardiac failure 22 Atheromatous disease and lipoprotein metabolism 23 Haemostasis and thrombosis 24 The haemopoietic system 25 Respiration, asthma and COPD 26 The kidney 27 The gastrointestinal tract 28 Blood sugar and diabetes 29 The anterior pituitary and the adrenal cortex 30 The thyroid 31 Bone metabolism 32 The reproductive system 33 Outline of transmission and drug action in the CNS 34 Aminoacid transmitters in the CNS 35 Other CNS transmitters 36 Neurodegenerative disorders 37 General anaesthetics 38 Anxiolytic and hypnotic drugs 39 Antipsychotic drugs 40 Drugs used in affective disorders 41 Antiepileptic drugs 42 Analgesic drugs and the control of pain 43 CNS stimulants and psychotomimetics 44 Local anaesthetics 45 Drug dependence and drug abuse 46 Cancer biology and chemotherapy 47 Antibacterial agents 48 Antiviral drugs 49 Antiprotozoal drugs 50 Antifungal and anthelminthic drugs Appendix 1: The Schild plot and pA2 Appendix 2: The postulated action of NSAIDs on the enzymes Cyclooxygenase-1 and Cyclooxygenasox-2 Appendix 3: The pathogenesis of rheumatoid joint damage and the action of anti-rheumatoid drugs Index