Progress and Challenges in Precision Medicine

Progress and Challenges in Precision Medicine

By: Debmalya Barh (editor), Mukesh Verma (editor)Paperback

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Progress and Challenges in Precision Medicine presents an insightful overview to the myriad factors of personalized and precision medicine. The availability of the human genome, large amounts of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the age of personalized and precision medicine. Bringing together a global range of experts on precision medicine, this book collects previously scattered information into one concise volume which covers the most important developments so far in precision medicine and also suggests the most likely avenues for future development. The book includes clinical information, informatics, public policy implications, and information on case studies. It is a useful reference and background work for students, researchers, and clinicians working in the biomedical and medical fields, as well as policymakers in the health sciences.

About Author

Dr. Mukesh Verma is a Program Director and Chief in the Methods and Technologies Branch (MTB), Epidemiology and Genetics Research Program (EGRP) of the Division of Cancer Control and Population Sciences (DCCPS) at the National Cancer Institute (NCI), National Institutes of Health (NIH). Before coming to the DCCPS, he was a Program Director in the Division of Cancer Prevention (DCP), NCI, providing direction in the areas of biomarkers, early detection, risk assessment and prevention of cancer, epigenetics, epidemiology, and cancers associated with infectious agents. Since joining the NCI, he has sought to champion the visibility of and investment in cancer epigenetics research both within the Institute and across other federal and non-governmental agencies, and to raise public awareness about controlling cancer. He represents NIH in Common Fund Programs on Epigenomics, Metabolomics, and Molecular Transducers of Physical Activity. Dr. Mukesh Verma holds a M.Sc. from Pantnagar University and a Ph.D. from Banaras Hindu University. He did postdoctoral research at George Washington University and was a faculty member at Georgetown University Medical Center. He has published 161 research articles and reviews and edited five books in cancer biomarkers, epigenetics and epidemiology field. Dr. Barh is a MSc (Applied Genetics), MTech & MPhil-(Biotechnology), PhD (Genomics), PhD (Biotechnology) and Post Graduate in Management. He has over 15 years leading healthcare, molecular diagnostic, bioinformatics industry and academic research experience in the field of integrative omics-based biomarkers, targets, targeted drugs, precision diagnosis, and personalized and predictive medicine in cancers and various complex diseases. Dr. Barh has edited 15+ cutting-edge research reference books in the field of omics and is a regular reviewer of various leading journals published by Nature publications, Biomed Central (BMC), PLOS etc. Due to his significant contribution in the field, he has been recognized by Who's Who in the World and Limca Book of Records. He is also the editor of the forthcoming Elsevier title Omics Technologies and Bio-Engineering (Jan 2017).


1. Introduction: Every Individual Is Different and Precision Medicine Offers Options for Disease Control and Treatment 2. Clinical Next-Generation Sequencing: Enabling Precision Medicine 3. Phenotyping in Precision Medicine 4. Cancer Genetic Screening and Ethical Considerations for Precision Medicine 5. Precision Medicine in Primary Health Care 6. Population Approach to Precision Medicine 7. Regulation of Genomic Testing in the Era of Precision Medicine 8. Image-Based Modeling and Precision Medicine 9. Sharing Outside the Sandbox? The Child's Right to an Open Data Sharing Future in Genomics and Personalized Medicine 10. Lessons Learned From Cohort Studies, and Hospital-Based Studies and Their Implications in Precision Medicine 11. Clinical Trials in Precision Medicine 12. Time to Educate Physicians and Hospital Staff in Electronic Medical Records for Precision Medicine 13. Computational Approaches in Precision Medicine 14. Handling Big Data in Precision Medicine 15. Trends in Precision Medicine 16. Personalized Medicine: Interdisciplinary Perspective, World Tidal Wave, and Potential Growth for the Emerging Countries

Product Details

  • ISBN13: 9780128094112
  • Format: Paperback
  • Number Of Pages: 344
  • ID: 9780128094112
  • weight: 540
  • ISBN10: 0128094117

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