This book presents the evidence for the belief that psoriasis is a disease of abnormal keratinocyte proliferation induced by T cells. The latest approaches to investigating the immunopathogenesis of this disease, and a review of previous findings, are presented to give an overall picture of the current knowledge in this field. Each topic is discussed in detail, clearly illustrated and well referenced. The book should prove invaluable to clinical dermatologists, and researchers in the fields of immunology and dermatology who have an interest in skin diseases.
Aetiology, clinical and histological features of psoriasis; skin immune system in psoriasis; immune cell function in psoriasis; psoriasis is a T cell-mediated disease; beta-haemolytic streptococci and psoriasis; immune function of psoriatic keratinocytes; current and future immunological approaches to treatment of psoriasis; model for immunopathogenesis of psoriasis.