This volume brings together the Perspectives and Topical Reviews published during 1998 in The Journal of Physiology, and the in-depth and authoritative Physiological Society Annual Review Prize Lectures from 1997 and 1998, with the intention of making their content as accessible as possible to both students and researchers in physiology. The Journal of Physiology publishes original research papers that illustrate new physiological principles and mechanisms, with an emphasis on human and mammalian physiology. It is among the most rapidly published journals in its field, and has one of the highest citation indexes in physiology.
Annual Review Prize Lectures: Elementary and global aspects of calcium signalling M. J. Berridge; Voltage-gated and inwardly rectifying potassium channels L. Y. Jan, Y. N. Jan; Topical Reviews: Mechanisms of modulation of voltage-dependent calcium channels by G proteins A. C. Dolphin; Structure and function of voltage-gated sodium channels E. Marban, T. Yamagishi, G. F. Tomaselli; Rhythmicity, synchronization and binding in human and primate motor systems S. F. Farmer; Hypoxia and smooth muscle function: key regulatory events during metabolic stress M. J. Taggart, S. Wray; Colour processing in the primate retina: recent progress P. R. Martin; Perspectives: The paradox of hair cell adaptation C. J. Kros; Two forms of triggered endocytosis in regulated secretory cells R. D. Burgoyne; Bayliss, myogenic tone and volume-regulated chloride channels in arterial smooth muscle M. T. Nelson; Which Ca2+ channels control cardiac E-C coupling? P. Lipp, M. D. Bootman; Ca2+-induced Ca2+ release: physiological experiments on a new level W. G. Wier; Synchronisation of somato-sympathetic outflows during exercise: role for a spinal rhythm generator J. T. Potts, J. H. Mitchell; Direct and indirect regulation of a single ion channel N. S. Magoski, L. K. Kaczmarek; The revival of the role of the mitochondrion in regulation of transmitter release N. Melamed-Book, R. Rahamimoff; Learning to cope with repeated stress G. Leng, J. A. Russell; K+-Cl- cotransport: 'to be or not to be' oxygen sensitive P. K. Lauf; The J reflex J. G. Widdicombe; A short-term mechanism of plasticity for interneurones? C. J. McBain; Ion channel activity drives ion channel expression A. B. Ribera; Muscle geometry R. McNeill Alexander; The generation of directionally selective responses in the retina S. C. Mangel; Another trigger for the heartbeat A. W. Trafford, D. A. Eisner; The continuing debate about CNS control of proprioception A. Prochazka, M. Hulliger; Cross-talk between apparently independent receptors T. J. Searl, E. M. Silinsky.