Featuring hundreds of full-color photomicrographs, Hematology: Clinical Principles and Applications prepares you for a job in the clinical lab by exploring the essential aspects of hematology. It shows how to accurately identify cells, simplifies hemostasis and thrombosis concepts, and covers normal hematopoiesis through diseases of erythroid, myeloid, lymphoid, and megakaryocytic origins. This book also makes it easy to understand complementary testing areas such as flow cytometry, cytogenetics, and molecular diagnostics. Well-known authors Bernadette Rodak, George Fritsma, and Elaine Keohane cover everything from working in a hematology lab to the parts and functions of the cell to laboratory testing of blood cells and body fluid cells.Instructions for lab procedures include sources of possible errors along with comments.Case studies in each chapter provide opportunities to apply hematology concepts to real-life scenarios.Hematology instruments are described, compared, and contrasted. UPDATED, full-color illustrations make it easier to visualize hematology concepts and show what you'll encounter in the lab, with images appearing near their mentions in the text so you don't have to flip pages back and forth.Hematology/hemostasis reference ranges are listed on the inside front and back covers for quick reference.A bulleted summary makes it easy to review the important points in every chapter.Learning objectives begin each chapter and indicate what you should achieve, with review questions appearing at the end.A glossary of key terms makes it easy to find and learn definitions. NEW coverage of hematogones in the chapter on pediatric and geriatric hematology helps you identify these cells, a skill that is useful in diagnosing some pediatric leukemias.UPDATED chapter on molecular diagnostics covers new technology and techniques used in the lab.
Part I: Introduction to Hematology1. An Overview of Clinical Laboratory Hematology2. Safety in the Hematology Laboratory3. Blood Specimen Collection4. Care and Use of the Microscope5. Quality Assurance in Hematology and Hemostasis TestingPart II: Blood Cell Production, Structure, and Function6. Cellular Structure and Function7. Hematopoiesis8. Erythrocyte Production and Destruction9. Erythrocyte Metabolism and Membrane Structure and Function10. Hemoglobin Metabolism11. Iron Kinetics and Laboratory Assessment12. Leukocyte Development, Kinetics, and Function13. Platelet Production, Structure, and FunctionPart III: Laboratory Evaluation of Blood Cells14. Manual, Semiautomated, and Point-of-Care Testing in Hematology15. Automated Blood Cell Analysis16. Examination of the Peripheral Blood Film and Correlation with the Complete Blood Count17. Bone Marrow Examination18. Body Fluid Analysis in the Hematology LaboratoryPart IV: Erythrocyte Disorders19. Anemias. Red Blood Cell Morphology and Approach to Diagnosis20. Disorders of Iron Kinetics and Heme Metabolism21. Anemias Caused by Defects of DNA Metabolism22. Bone Marrow Failure23. Introduction to Increased Destruction of Erythrocytes24. Intrinsic Defects Leading to Increased Erythrocyte Destruction25. Extrinsic Defects Leading to Increased Erythrocyte Destruction - Nonimmune Causes26. Extrinsic Defects Leading to Increased Erythrocyte Destructions - Immune Causes27. Hemoglobinopathies (Structural Defects in Hemoglobin)28. ThalassemiasPart V: Leukocyte Disorders29. Nonmalignant Leukocyte Disorders30. Cytogenetics31. Molecular Diagnostics in the Clinical Laboratory32. Flow Cytometric Analysis in Hematologic Disorders33. Myeloproliferative Neoplasms34. Myelodysplastic Syndromes35. Acute Leukemias36. Mature Lymphoid NeoplasmsPart VI: Hemostasis and Thrombosis37. Normal Hemostasis and Coagulation38. Hemorrhagic Disorders and Laboratory Assessment39. Thrombotic Disorders and Laboratory Assessment40. Thrombocytopenia and Thrombocytosis41. Qualitative Disorders of Platelets and Vasculature42. Laboratory Evaluation of Hemostasis43. Measuring Antithrombotic Therapies44. Hemostasis and Coagulation InstrumentationPart VII: Hematology and Hemostasis in Selected Populations45. Pediatric and Geriatric Hematology and HemostasisAppendix